PSORIASIS (PSO)

This early-stage study tests a new oral drug, LPX-TI641, in 48 adults with atopic dermatitis (eczema) or psoriasis. The main goal is to check if the drug is safe and tolerable compared to a placebo over 28 days. Researchers will also measure how the drug moves through the body. T…

This study tests a new medicine called HB0017 for people with moderate to severe plaque psoriasis. About 200 adults will receive different doses of the injection to see how well it clears skin and how safe it is. The goal is to find the best dosing schedule for this chronic skin …

This study is testing whether semaglutide (a drug used for diabetes and weight loss) can improve psoriasis when added to a standard topical cream. About 62 adults with plaque psoriasis who are overweight or have type 2 diabetes will take either semaglutide or a placebo pill for 1…

This early-phase study tests whether taking probiotics alongside methotrexate can improve psoriasis symptoms and gut bacteria in newly diagnosed adults. Twenty-four participants will take either probiotics plus methotrexate or methotrexate alone for 4 months. Researchers will com…

This study tests whether a dermatologist's physical exam or a patient questionnaire is better at finding psoriatic arthritis (PsA) in people with psoriasis. About 500 adults with psoriasis will be screened both ways, then checked by a rheumatologist for a final diagnosis. The goa…

This study is testing an oral medication called roflumilast to see if it can safely reduce psoriasis symptoms in adults with moderate-to-severe plaque psoriasis. Over 12 weeks, 36 participants will take the drug daily, starting with a low dose and increasing it. The main goal is …

This study observes 80 adults in Canada with moderate-to-severe psoriasis who are starting tildrakizumab as part of their routine care. Researchers will track changes in quality of life and skin clearance over 52 weeks, focusing on people with Fitzpatrick skin types III and above…