PSORIASIS (PSO)

This small, early-stage study is investigating whether taking probiotic supplements alongside the standard psoriasis drug methotrexate can help patients get better results. Researchers will compare two groups of 24 newly diagnosed adults: one taking methotrexate plus probiotics, …

This study is testing an experimental injection called HB0017 for people with moderate to severe plaque psoriasis. It aims to find the best dosing schedule by measuring how much it improves skin symptoms and how safe it is. About 200 participants will be randomly assigned to rece…

This study is observing how well an already-approved psoriasis medication works for people in their everyday lives in Canada. It will follow about 80 adults with moderate-to-severe psoriasis who are starting this specific treatment as part of their normal care. The main goal is t…

This study is testing if an oral medication called roflumilast is safe and can help improve moderate-to-severe plaque psoriasis. For 12 weeks, 36 adult participants will take the pill daily. Researchers will measure changes in skin symptoms and monitor for side effects to see if …

This study is testing if adding the drug semaglutide, which is used for diabetes and weight loss, to standard psoriasis skin cream can better control the skin disease. It will involve 62 adults with plaque psoriasis who are also overweight or have type 2 diabetes. Researchers wil…

This is an early-stage study to check the safety and how the body processes a new oral drug called LPX-TI641. It will involve about 48 adults with moderate-to-severe eczema (atopic dermatitis) or plaque psoriasis. Participants will take the drug or a placebo pill daily for 28 day…

This study aims to find the best way to identify psoriatic arthritis early in people who have psoriasis. It will compare two methods: a standard patient questionnaire versus that same questionnaire plus a brief joint check by a dermatologist. The goal is to see which approach mor…