PRETERM NEONATE

This study compares two sedatives—dexmedetomidine and midazolam—in very premature babies (born before 32 weeks) who need a breathing machine. The goal is to see if dexmedetomidine helps them come off the ventilator faster, reducing lung damage and side effects. About 380 babies w…

This study tests whether using lung ultrasound instead of chest X-rays can safely reduce radiation exposure in very preterm babies (born before 32 weeks) who need breathing support. About 180 infants will be randomly assigned to get either standard chest X-rays or lung ultrasound…

This study looks at how different levels of gentle breathing support (called PEEP/CPAP) affect the lungs of babies born before 32 weeks. The goal is to find the best pressure to keep their tiny lungs open and reduce the need for a breathing machine. Researchers will use a new, ra…

This study watches how doctors decide when to remove breathing tubes (extubation) in extremely preterm babies (born before 28 weeks) during their first two weeks of life. Researchers will ask doctors daily why they choose to keep or remove the tube, and track whether the baby sta…

This study looks at how hard premature babies (born at 32 weeks or earlier) have to work to breathe just before and just after their breathing tube is removed. Researchers want to see if these breathing effort measurements can better predict which babies will need the tube put ba…