PREGNANCY RELATED

This study tests whether delivering healthy meals to the homes of pregnant women with overweight or obesity can help them avoid gaining too much weight during pregnancy. Researchers will track weight changes and also look at food security and stress levels. The study involves 35 …

This study tests whether a special team of doctors and nurses can reduce deaths in pregnant women with sickle cell disease (SCD) and their babies. About 500 pregnant women with SCD in Ghana will receive coordinated care from SCD and pregnancy experts. The program focuses on preve…

This study looks at whether a daily probiotic supplement can improve blood sugar control and limit weight gain in pregnant women who are overweight. About 84 women in early pregnancy will take the supplement or a placebo. The goal is to see if probiotics can help manage metabolic…

This study tests whether a weight loss program for overweight or obese women (and their partners) before pregnancy can reduce the risk of their child becoming overweight. 240 couples are randomly assigned to either a very low-calorie diet and counseling or no intervention. The ma…

This study tests whether giving vitamin B12 supplements to pregnant women at risk of deficiency can improve their children's brain development and growth. Researchers will give 800 pregnant women in South Asia either a daily B12 pill or a placebo from early pregnancy until six mo…

This study tests whether helping women with overweight or obesity adopt a healthy lifestyle before and during pregnancy can reduce the risk of their children developing obesity. About 360 women planning pregnancy will either receive a tailored program including a low-calorie diet…

This study tests a mobile app called Next4You designed for teens aged 16-19 in California's foster care system. The app includes short lessons to help youth make informed choices about sex, with the goal of reducing unintended pregnancies and sexually transmitted infections. Rese…

This study tests whether a simplified behavioral relaxation program can improve sleep in pregnant women with insomnia. Twenty women in their second or third trimester will receive coaching calls and sleep hygiene tips. The goal is to see if this approach helps them fall asleep fa…

This study tests whether a prenatal yoga app called Down Dog can improve well-being in 50 pregnant African American women. Participants use the app for at least 20 minutes, three days a week, for 12 weeks. The goal is to see if the app is easy to use and helps with stress, depres…

This study tests a group prenatal care program called EleVATE GC for African-American women at high risk for postpartum depression. The program aims to reduce depression, preterm birth, and low birthweight by providing support and addressing stress. Researchers will compare outco…

This study tests a program called Well-Mama, where community doulas use a checklist to support pregnant and postpartum women. The goal is to see if this extra support helps women get better care and feel more in control of their health. About 576 pregnant women on Medicaid will b…

This study reviews medical records of 2,500 pregnant women to see if insurance status affects how well pain relief (epidural) works during emergency C-sections. Researchers want to uncover hidden healthcare gaps on the labor floor. The study does not test any new treatment—it sim…

This study examines head and neck cancers that occur during pregnancy or within 12 months after giving birth. Researchers will check for certain viruses (HPV and EBV) and look at tumor types and pregnancy complications. The goal is to better understand these rare cases, not to te…

This study follows 180 pregnant women to see how changes in their body fat during pregnancy relate to their baby's body fat at birth. Researchers use MRI scans and weight tracking to understand early influences on childhood obesity. The goal is to learn more about how the womb en…

This registry enrolls up to 1,000 women aged 12–55 with rheumatic or autoimmune diseases who are pregnant or planning pregnancy. Researchers will collect data from medical records and patient surveys to study pregnancy outcomes, disease activity, and medication use. No experiment…

This study was designed to see if giving pregnant women nutrition advice based on their unique biology, lifestyle, and health could improve their health and their baby's health. It planned to enroll women less than 20 weeks pregnant, excluding those with high-risk conditions. How…

This study looks at how eating fermented and fiber-rich foods during pregnancy changes the gut bacteria of mothers and their babies. Researchers will track 135 pregnant women and their infants to see if diet affects the types of bacteria passed from mom to baby. The goal is to le…

This study is a registry that collects information from 75 pregnant women with heart disease across the United States. The goal is to better understand how heart conditions affect mothers and their babies during pregnancy and for up to five years after birth. Researchers will als…

This study tests whether community health workers can help pregnant people on Medicaid get better access to nutritious food. About 124 participants will receive support from a health worker and be tracked for changes in food security, mood, social support, and baby's health at bi…

This study tests whether a culturally tailored mobile health program can improve mental health and pregnancy outcomes in Black pregnant women. Half of the 150 participants will receive the program, which builds communication and self-advocacy skills and provides support. The goal…

This study aimed to develop better MRI scanning methods for imaging fetuses during pregnancy. The goal was to improve image quality and make scans faster and more accurate, even when the baby moves. However, the study was withdrawn before any participants were enrolled, so no res…

This study tests a program to help prenatal clinics improve how they measure and manage high blood pressure in pregnant and postpartum patients. About 4,000 clinic staff and providers in North Carolina will receive training, coaching, and tools to better recognize and treat sever…

This study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…

This study looks at health records from 10 pregnant women with opioid use disorder to find ways to improve care for both mother and baby. The goal is to use this information to create better treatment programs and reduce problems like neonatal withdrawal syndrome. The study does …

This study follows 285 pregnant women with cystic fibrosis to see how their lung function changes during pregnancy and for two years after giving birth. Researchers are focusing on those taking highly effective CFTR modulators. The goal is to better understand the effects of preg…

Many pregnant women have experienced trauma, which can make prenatal care stressful and increase health risks. This study will create and test a toolkit to train obstetric providers in trauma-informed care, including screening tools and modified procedures. Researchers will work …

This study looks at how well pregnant women in Tanzania like and tolerate different amounts of iron in their daily prenatal vitamins. 156 women will try three different iron doses (30 mg, 45 mg, and 60 mg) and report which one they prefer and any side effects. The goal is to find…