Pregnancy complications

This study looks at whether starting daily low-dose aspirin in the first trimester (weeks 1–12) is safer and more effective than starting in the second trimester (weeks 13–27) for pregnant women with sickle cell disease. Researchers will track maternal deaths, preterm births, and…

This study tests whether adding a specially trained doula, along with home blood pressure and weight monitoring, can improve blood pressure in women who had high blood pressure during pregnancy. About 454 women will be randomly assigned to usual care or the doula program. The goa…

This study looked at a fetal surgery called fetoscopic laser photocoagulation (FLP) to treat vasa previa, a condition where fetal blood vessels cover the womb opening, making vaginal delivery dangerous. The goal was to seal off these vessels to prevent bleeding and allow a safer …

This study tests whether adding Moringa leaf powder to standard iron pills can better improve hemoglobin levels in pregnant women with iron deficiency anemia. About 59 women in their third trimester will take either Moringa capsules plus iron or iron alone for 60 days. Researcher…

This study tests whether women with high-risk pregnancies can safely monitor their baby's heart rate and their own blood pressure from home instead of going to the hospital. About 450 participants across four European hospitals will use certified home devices, with data reviewed …

This study tests whether giving pregnant women a heart ultrasound during routine check-ups can catch hidden heart problems and reduce risks like death, heart failure, or low baby health scores. About 9,000 women in Nepal will be randomly assigned to receive the ultrasound or stan…

This study tests whether a more intensive diet and activity counseling program can help high-risk pregnant women keep their blood sugar in a healthy range and lower their chances of developing gestational diabetes. About 100 women early in pregnancy (16 weeks or less) who have ri…

This study tests whether providing money specifically for healthy foods during pregnancy helps minority and rural women in Arkansas avoid gaining too much weight. About 280 pregnant women will either receive standard nutrition advice or that advice plus funds to buy recommended h…

This study tests whether starting nutritional counseling early in pregnancy can improve blood sugar control in women at risk for gestational diabetes. 150 pregnant women will receive either standard care or one-on-one sessions with a dietitian, plus videos and phone support. The …

This study tests whether a physical activity program can help pregnant people with symptoms of depression or anxiety feel better. 88 participants will be given a step goal and wear an activity tracker. The program includes weekly reminders and motivational coaching every two week…

This study looks at how the bacteria in a pregnant woman's gut (her microbiome) and her nutrition affect her baby's growth and health. Researchers are following 800 young pregnant women (28 and under) in Toronto throughout pregnancy and for a year after birth. They collect stool,…

This study tests whether a culturally tailored mobile health program can improve mental health and pregnancy outcomes in Black pregnant women. Half of the 150 participants will receive the program, which builds communication and self-advocacy skills and provides support. The goal…