PREGABALIN

This study tests whether adding dexmedetomidine (a drug that helps with sleep) to standard pregabalin treatment provides better pain relief for people with fibromyalgia. About 400 adults with moderate to severe pain will be enrolled. The goal is to see if the combination works be…

This study compares pregabalin alone versus pregabalin plus desvenlafaxine for treating fibromyalgia, a condition causing widespread pain and fatigue. Researchers will enroll 384 adults with moderate to severe pain that hasn't improved with non-drug treatments. The goal is to see…

This study compares two medications, pregabalin and a newer drug called crisugabalin, to see which works better for easing fibromyalgia pain. Over 1,100 adults with moderate to severe fibromyalgia will take one of the two drugs, and researchers will measure how many get at least …

This study compares taking pregabalin alone versus pregabalin plus toludesvenlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The study will enroll 384 adu…

This study looks at whether adding esketamine to standard fibromyalgia treatments can reduce pain more quickly and effectively. About 92 adults with fibromyalgia who haven't gotten enough relief from other treatments will take part. Researchers will compare pain levels between th…

This study compares two medications, pregabalin and mirogabalin, to see which works better for easing fibromyalgia pain. About 674 adults with moderate to severe fibromyalgia will take one of the drugs and report their pain levels. The goal is to find a more effective and safer t…

This study compares taking pregabalin alone versus pregabalin plus venlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The study will enroll 750 adults wit…

This study tests whether adding amantadine or duloxetine to the standard painkiller pregabalin can prevent chronic pain after mastectomy. About 150 women undergoing breast cancer surgery will be randomly assigned to one of three drug combinations. The goal is to see if these add-…

This study tests a new drug called Y-4 for people with long-term nerve pain after shingles (postherpetic neuralgia). About 160 adults will take either Y-4 or the standard drug pregabalin for 14 weeks. Researchers will check if Y-4 reduces daily pain better and is safe to use.

This study tests whether melatonin (a natural sleep hormone) works as well as pregabalin (a nerve pain drug) for managing pain and anxiety after spine surgery. About 105 adults aged 21-60 having elective spine surgery will receive one of the two medicines right after surgery. Res…