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New hope for fibromyalgia? study tests Two-Drug approach for pain

NCT ID NCT07171320

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 35 times

Summary

This study compares pregabalin alone versus pregabalin plus desvenlafaxine for treating fibromyalgia, a condition causing widespread pain and fatigue. Researchers will enroll 384 adults with moderate to severe pain that hasn't improved with non-drug treatments. The goal is to see if the combination offers better pain relief without more side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Beijing, Beijing 100070

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pregabalin and desvenlafaxine

What this could lead to

If successful, this could offer a more effective pain relief option for people with fibromyalgia who don't get enough help from pregabalin alone.

What could go wrong

This is an early-stage study with no phase designation, so results are uncertain. The combination may not provide significantly better pain relief and could cause more side effects.

Conditions

The condition(s) this trial relates to.

fibromyalgia Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.