PREGABALIN

This study compares taking pregabalin alone versus pregabalin plus toludesvenlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. About 384 adults with moderate to severe pain that hasn't improved with other treatments will participate. The goal is to see i…

This study compares the standard drug pregabalin alone versus pregabalin combined with dexmedetomidine for treating fibromyalgia, a condition causing widespread pain and fatigue. Researchers hope the combination will provide greater pain relief without more side effects. The tria…

This study tests whether melatonin (a natural sleep hormone) works as well as pregabalin (a nerve pain drug) for reducing pain and anxiety after spine surgery. About 105 adults aged 21-60 having elective spine surgery will be randomly assigned to receive one of the two medicines.…

This study looks at whether adding esketamine to usual fibromyalgia treatments can reduce pain more effectively and faster. About 92 adults with fibromyalgia who haven't gotten enough relief from standard care will take part. Researchers will compare pain scores between those get…

This study tests a new drug called Y-4 to see if it works better than the standard medicine pregabalin for long-term nerve pain after shingles (postherpetic neuralgia). About 160 adults with pain lasting more than a month after their rash healed will take either Y-4 or pregabalin…

This study compares two medications, pregabalin and a newer drug called crisugabalin, to see which works better for fibromyalgia pain. Fibromyalgia causes widespread pain, fatigue, and emotional distress. The trial will include 1,116 adults with moderate to severe pain who haven'…

This study tests two medications, pregabalin and mirogabalin, to see which one better reduces pain in people with fibromyalgia, a condition causing widespread pain and fatigue. About 674 adults with moderate to severe fibromyalgia will take one of the drugs and report their pain …

This study compares pregabalin alone versus pregabalin plus venlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The trial will enroll 750 adults with moder…

This study tests whether adding amantadine or duloxetine to the standard painkiller pregabalin can prevent chronic pain after mastectomy (breast removal surgery). About 150 women undergoing this surgery will be randomly assigned to one of three drug combinations. The goal is to s…

This study compares taking pregabalin alone versus pregabalin combined with desvenlafaxine for fibromyalgia, a condition causing widespread pain and fatigue. Researchers want to see if the combination provides better pain relief without more side effects. The study will involve 3…