POSTPARTUM HEMORRHAGE

This study tests a device called AAJT-S, a temporary abdominal tourniquet, to quickly stop severe bleeding after childbirth when standard treatments don't work. About 20 women with heavy bleeding will have the device placed around their belly and inflated. The goal is to see if b…

This study looks at whether draining the umbilical cord after a vaginal birth can lower the chance of severe bleeding (postpartum hemorrhage). About 400 pregnant women having a normal delivery will be randomly assigned to either have cord drainage or not. Researchers will measure…

This study aims to find the smallest effective dose of oxytocin to prevent heavy bleeding after a C-section in women who have been in labor. Oxytocin helps the uterus contract and reduce blood loss. Researchers will adjust the dose for each new participant based on how the previo…

This study tests a device called KOKO to see if it can safely and effectively stop heavy bleeding after childbirth. About 72 women who experience abnormal bleeding or hemorrhage within 24 hours of giving birth will be enrolled. The device is used to control bleeding and avoid the…

This study tests whether giving a clotting protein called factor XIII early can reduce blood loss in women with heavy bleeding after childbirth. About 988 women having a vaginal delivery in Switzerland will take part. Those who continue bleeding after standard care will either re…

This study tests a new care plan called 'Rule of THUMB' to help doctors better manage heavy bleeding during and after C-sections. About 2,400 women having C-sections in African hospitals will take part. The plan includes checking bleeding risk, giving medicines, and ensuring foll…

This study checks if a quick, bedside test (qLabs®FIB) can accurately measure fibrinogen levels in women with severe postpartum hemorrhage. Low fibrinogen is a warning sign for dangerous bleeding. The goal is to see if this faster test can help doctors make treatment decisions so…

This study tests whether the drug carbetocin works better than standard oxytocin to prevent heavy bleeding after twin deliveries. Heavy bleeding is more common with twins and can cause serious health problems. About 120 pregnant people with twins will be randomly assigned to rece…

This study uses tiny samples of uterine tissue from women having planned C-sections to test which backup drug best helps the uterus contract after carbetocin. The goal is to find the most effective treatment to prevent severe bleeding after childbirth. About 32 women will provide…

This study looks at how three common blood pressure drugs (ephedrine, phenylepinephrine, and norepinephrine) affect the ability of the uterus to contract after a C-section in women with type 2 or gestational diabetes. Researchers will take small samples of uterine tissue during t…

This study looks back at medical records of 648 women who had a C-section and heavy bleeding after birth. Researchers want to see how often the drug tranexamic acid (TXA) was given over the years and how it affected blood loss and the need for transfusions. The goal is to underst…

This study compares a serious video game to traditional teaching for nursing students learning how to handle postpartum hemorrhage (heavy bleeding after childbirth). About 70 third-year nursing students will be split into two groups: one gets the game-based training plus standard…

This study looks at whether opening the clamp on the umbilical cord after cutting it (called placental cord drainage) can shorten the time it takes for the placenta to come out and reduce blood loss after birth. About 80 low-risk pregnant women having a normal vaginal delivery wi…