Lab study aims to find best backup drug for Post-Birth bleeding
NCT ID NCT06285409
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses small samples of uterine tissue from 32 women having planned C-sections to test which backup drug best contracts the uterus after carbetocin has been given. The goal is to improve treatment for severe bleeding after childbirth. The research is done in the lab, not on patients directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 32 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria * Patients who give written consent to participate in this study * Patients with gestational age 37-41 weeks * Non-laboring patients, not exposed to exogenous oxytocin * Patients requiring elective primary or first repeat CD * Patients undergoing CD under spinal anesthesia Exclusion criteria * Patient refusal * Patients who require general anesthesia * Patients in labour and those receiving oxytocin for induction of labour * Emergency CD * placenta accreta spectrum disorder * Patients who have had previous uterine surgery or \>1 previous CD * Patients with any condition predisposing to uterine atony and PPH (BMI \> 40 kg/m2, * Patients on medications that could affect myometrial contractility, such as insulin, nifedipine, labetalol or magnesium sulphate.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mount Sinai Hospital
RECRUITINGToronto, Ontario, M5G1X5, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a slower oxytocin infusion prevent dangerous blood pressure drops in C-Sections?
- A 12-minute video could save new mothers' lives – can it teach them to spot danger?
- Can a simple calcium tablet help prevent postpartum bleeding?
- Medical glue vs. internal bleeding: a new hope?
- Which drug stops Post-Birth bleeding better? a Head-to-Head test
- Could a simple calcium injection prevent dangerous bleeding after childbirth?