POSTOPERATIVE PAIN MANAGEMENT

This study looks at 27 adults having lung surgery to find the smallest amount of numbing medicine (bupivacaine) that works well for pain. Doctors will adjust the dose for each person to see what provides good pain relief. The goal is to manage pain effectively while using as litt…

This study tests two ways to manage pain after keyhole hysterectomy: a spinal injection of morphine before surgery, or numbing medicine injected into the belly at the end. Researchers will track recovery quality, pain levels, and side effects in 64 women. The goal is to find whic…

This study tests a non-invasive device that gently stimulates a nerve in the ear to see if it can lower inflammation and pain after major spine surgery. Researchers will measure inflammatory markers and pain scores in 50 adults undergoing long-segment spinal fusion. The goal is t…

This study tests two different ways to numb the back of the knee after total knee replacement surgery. Both methods are combined with a standard front-of-thigh block. The goal is to see which approach provides better pain control, helps patients move sooner, and improves overall …

This study compares two ways to manage pain after umbilical hernia surgery: a TAP block (an ultrasound-guided injection into the abdominal wall) and a single-dose epidural block. Researchers will measure pain levels in 30 adults at different times after surgery to see which metho…

This study looks at whether adding a TAP block (a numbing injection in the belly wall) to standard spinal morphine helps women feel better and recover faster after a planned C-section. About 150 women will take part, and researchers will measure pain, opioid use, and recovery qua…

This study tests whether a drug called Anrikefon can control pain after eye surgery as well as the standard painkiller nalbuphine, but with fewer side effects like drowsiness or dizziness. About 204 adults having eye surgery under general anesthesia will receive either Anrikefon …

This study looks at whether adding dexmedetomidine to a standard numbing medicine (ropivacaine) in a nerve block can improve pain relief after hip replacement surgery. About 120 adults having hip surgery will be randomly assigned to receive either the standard nerve block or the …

This study tests whether giving a combination of two drugs (lidocaine and dexmedetomidine) during laparoscopic weight-loss surgery can reduce pain, inflammation, and oxidative stress afterward. About 104 adults having bariatric surgery will be randomly assigned to receive the com…

This study tests two pain medicines, dezocine and nalbuphine, given with a standard opioid after oral cancer surgery. The goal is to find which combination controls pain better, causes fewer side effects like nausea, and helps the surgical flap heal. Sixty adults aged 18 to 70 ha…

This study looks at whether teaching people about how pain works (called Pain Neuroscience Education) can improve recovery after rotator cuff surgery. About 45 adults aged 40-75 will be split into three groups: standard rehab, or standard rehab plus pain education either before o…

This study compares two types of ultrasound-guided pain blocks given before lumbar microdiscectomy surgery to see which one better controls pain and reduces the need for opioids. Eighty adults aged 18 to 65 will be randomly assigned to receive one of the two blocks. The goal is t…

This study compares two types of nerve blocks for pain after hip replacement surgery. About 118 adults will receive either an iliopsoas plane block or a PENG block before surgery. The goal is to see if the newer block works as well for pain control and recovery.

This study tests a new medicine called HSK21542 for pain after hip replacement surgery. About 405 adults will get either HSK21542, morphine, or a placebo. The goal is to see if HSK21542 controls pain better and causes fewer side effects like nausea and vomiting.

This study compares two types of nerve blocks (ESPB and SPSIPB) to see which provides better pain relief for adults aged 45-85 undergoing heart bypass surgery. 64 participants will be randomly assigned to receive one of the blocks, and their pain levels, opioid use, and recovery …

This study looks at whether taking sitz baths (soaking the pelvic area in warm water) after surgery for pelvic organ prolapse helps reduce pain and improve recovery. About 112 women will be randomly assigned to either a sitz bath routine or standard care. The main goal is to meas…

This study tests two sedative drugs, remimazolam and midazolam, in 120 adults aged 65 and older having orthopedic surgery with regional anesthesia. The goal is to see which drug provides better sedation and causes fewer memory or thinking problems shortly after surgery. Neither p…

This study looks at whether using ultrasound-guided nerve blocks for pain relief after major abdominal surgery can lower the chance of lung complications. Researchers will observe 500 adults aged 65 and older who are having elective surgery. The study does not assign treatments; …

This study looks at two different numbing methods (nerve blocks) used during gallbladder removal surgery. Researchers will map where on the skin each block works and how long the numbness lasts. The goal is to better understand these blocks so doctors can choose the best one for …