Researchers watch and learn: do nerve blocks protect lungs after big surgery?
NCT ID NCT07394816
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study watches 500 adults aged 65 and older who are having major abdominal surgery. It compares those who get an ultrasound-guided nerve block for pain relief to those who get standard pain management. The goal is to see if the nerve block group has fewer lung complications within the first week after surgery. No new treatments are given—the study just observes what happens in regular hospital care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of patients aged 65 years and older who are scheduled to undergo elective major abdominal surgery under general anesthesia. Eligible participants will be managed in a tertiary care hospital and will be allocated to either a fascial plane block group or a control group receiving standard perioperative analgesia. The study aims to evaluate postoperative outcomes in an elderly surgical population with comparable baseline characteristics.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 65 years or older * Scheduled for elective major abdominal surgery (e.g., colorectal, hepatobiliary, pancreatic, or gastric surgery) * ASA physical status II-III * Ability to provide written informed consent * Planned use of general anesthesia with or without adjunct regional techniques Exclusion Criteria: * Refusal or inability to provide informed consent * Known allergy or contraindication to local anesthetics * Coagulopathy or ongoing anticoagulant therapy contraindicating regional anesthesia * Infection at the site of planned block * Pre-existing chronic opioid use or chronic pain syndrome * Severe hepatic, renal, or cardiac failure (e.g., Child-Pugh C, end-stage renal disease, EF \<30%) * Cognitive impairment or severe dementia preventing adequate pain assessment * Emergency surgery * Body mass index (BMI \> 40 kg/m²)
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital
RECRUITINGYenimahalle, Ankara, 06370, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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