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Ultrasound could reveal hidden lung changes after surgery

NCT ID NCT04677309

Knowledge-focused Sponsor: Ana Broseta Lleó Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses lung ultrasound to measure how the lungs change after surgery to remove part of a lung due to cancer. Researchers will check lung aeration before surgery, right after, and 24 hours later in about 32 adults. They aim to see if ultrasound findings relate to oxygen levels and other health markers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better predict and manage lung complications after surgery using a simple ultrasound.
What could go wrong
This is a small pilot study with only 32 participants, so results may not apply to all patients. It is observational, not testing a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

32 people

The number who actually took part.

Started

Dec 2020

Finished

Apr 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled for elective lung resection surgery at a tertiary referral hospital.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \> 18 * ASA I-III * Non-small cell lung neoplasm * Elective lobectomy * Under one-lung ventilation Exclusion Criteria: * pregnancy * Diagnosed pulmonary fibrosis * Scheduled surgery limited to biopsy * Surgery that includes resection of the thoracic wall or the diaphragm * Predicted FEV1 \< 40% * Neoplasm metastasis * Obesity class II or more (BMI ≥ 35 kg/m\^2) * Risk of malnutrition CONUT score \> 1 * Hemoglobin \< 10 g/dl * Chronic kidney failure: glomerular filtration \< 60 ml/min/m\^2, nephrectomy, kidney transplantation * Treatment with corticosteroids or immunosuppressive agents 3 months before surgery * Transfusion of blood products during the previous 10 days * Heart failure (New York Heart Association Functional Class 3 or 4) during the week before surgery. * Heart valve diseases over stage B of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines 2014 * Previously documented elevated left atrial pressure or cardiac disease associated with elevated left-sided filling pressures.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer Lung neoplasm Lung resection surgery Lung ultrasound Lung ultrasound score One-lung ventilation (OLV) Postoperative pulmonary complications (PPCS) Thoracic surgery

Contacts and locations

Locations

  • Hospital General Universitario de Valencia

    Valencia, Valencia, 46014, Spain

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