PERIPHERAL ARTERY DISEASE
Clinical trials for PERIPHERAL ARTERY DISEASE explained in plain language.
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New balloon could clear blocked leg arteries without major surgery
Disease control ENROLLING_BY_INVITATIONThis study looks at a new balloon device to treat hardened arteries in the legs. It will include 58 people with moderate to severe blockages. The balloon is designed to crack hard calcium deposits and improve blood flow. Researchers will check how well it works and if it is safe …
Matched conditions: PERIPHERAL ARTERY DISEASE
Sponsor: The First Affiliated Hospital of Dalian Medical University • Aim: Disease control
Last updated May 26, 2026 02:54 UTC
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New balloon treatment could help millions with clogged leg arteries
Disease control OngoingThis study is testing a special balloon coated with a drug that slowly releases medication to keep leg arteries open in people with peripheral artery disease. About 723 participants will receive the balloon treatment and be followed for one year to see if it reduces the need for …
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: NA • Sponsor: M.A. Med Alliance S.A. • Aim: Disease control
Last updated May 26, 2026 02:46 UTC
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Balloon battle: which coating keeps leg arteries open longer?
Disease control OngoingThis study compares two types of drug-coated balloons used to open blocked arteries in the leg due to peripheral artery disease. About 478 adults with moderate symptoms will be randomly assigned to receive either a sirolimus-coated or a paclitaxel-coated balloon. The main goal is…
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: NA • Sponsor: Jena University Hospital • Aim: Disease control
Last updated May 26, 2026 02:45 UTC
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New balloon coated with drug could save legs from amputation
Disease control OngoingThis study compares a special balloon coated with sirolimus (a drug that helps keep arteries open) to a standard balloon for treating blocked arteries below the knee in people with peripheral artery disease. About 230 participants will be randomly assigned to one of the two treat…
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: NA • Sponsor: Jena University Hospital • Aim: Disease control
Last updated May 26, 2026 02:44 UTC
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Handheld scanners could spot silent killers before symptoms start
Diagnosis ENROLLING_BY_INVITATIONThis study tests if portable devices like handheld ultrasound and blood glucose monitors can find chronic diseases such as diabetes, heart disease, and kidney disease earlier than standard care. About 200 adults aged 18 to 75 will use these devices or receive usual care for 6 mon…
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: EARLY_PHASE1 • Sponsor: Truway Health, Inc. • Aim: Diagnosis
Last updated May 26, 2026 02:43 UTC
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Can a simple therapy help leg pain sufferers walk pain-free?
Symptom relief OngoingThis early-stage study tests a combination therapy called ATLAS in 10 people with leg pain caused by narrowed arteries (peripheral artery disease). The goal is to see if it boosts a natural chemical that improves blood flow and helps people walk longer without pain. Participants …
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: PHASE1 • Sponsor: Louis Messina • Aim: Symptom relief
Last updated May 26, 2026 02:46 UTC
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Veterans with leg pain may walk better with telehealth exercise
Symptom relief OngoingThis study tests whether a telehealth exercise program can help veterans with peripheral artery disease (PAD) walk farther and feel better. About 73 veterans with PAD will participate from home. The program aims to improve walking ability, quality of life, and overall health with…
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Heart study for veterans with leg artery disease pulled before start
Knowledge-focused TerminatedThis study planned to find better ways to manage heart disease in veterans with severe peripheral artery disease (poor leg blood flow) after they had leg surgery. It aimed to reduce heart attacks and heart-related deaths in this high-risk group. However, the study was withdrawn b…
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 26, 2026 02:54 UTC
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Tiny wireless sensor tracks oxygen in legs of PAD patients
Knowledge-focused OngoingThis study tests a new wireless sensor that is injected under the skin to measure oxygen levels in the legs of people with peripheral artery disease (PAD). The sensor works with a small patch and app to track oxygen changes during simple maneuvers like using a pressure cuff. The …
Matched conditions: PERIPHERAL ARTERY DISEASE
Phase: NA • Sponsor: Profusa, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 02:51 UTC
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New registry tracks safety of GORE VIABAHN device in real patients
Knowledge-focused OngoingThis study is a global registry that collects information on patients who have been treated with the GORE VIABAHN endoprosthesis with PROPATEN bioactive surface. The goal is to see how safe the device is in real-world use by tracking serious side effects related to the device. Ab…
Matched conditions: PERIPHERAL ARTERY DISEASE
Sponsor: W.L.Gore & Associates • Aim: Knowledge-focused
Last updated May 11, 2026 20:49 UTC