OVERACTIVE BLADDER

This study is testing if a medication called Mirabegron, usually used for overactive bladder, can help slow the progression of dry age-related macular degeneration (AMD), a leading cause of vision loss. Researchers will compare it to another bladder drug (Solifenacin) in 312 olde…

This study aims to see if following up with patients at home works as well as bringing them back to the hospital after they receive bladder injections for overactive bladder. Researchers will give 112 patients connected devices to track their urination patterns and symptoms from …

This study aims to see if a mix of nitrous oxide and oxygen gas (often called laughing gas) can help reduce pain during Botox injections into the bladder. Researchers will compare the gas to a placebo (sham mask) in about 96 women who are already scheduled to get the injections. …

This study aims to see if combining two existing drugs, solifenacin and gabapentin, is more effective and safe for treating overactive bladder in women than using solifenacin alone. It will involve 60 women with bothersome bladder symptoms. Researchers hope the combination target…

This study is testing whether combining two approaches works better for Parkinson's patients with overactive bladder symptoms when one treatment alone isn't enough. Researchers will give 146 veterans with Parkinson's either pelvic floor exercises or medication first, then add the…

This study aims to understand how two major weight loss approaches—new medications like GLP-1 agonists and bariatric surgery—affect pelvic floor symptoms such as bladder leaks, urgency, and bowel control. It will follow 200 women with obesity who are starting either medication or…

This study aims to adapt and test a Turkish version of a questionnaire that measures the severity of urinary urgency and its impact on daily life. Researchers will enroll 130 Turkish-speaking women with overactive bladder to see if the translated questionnaire is reliable and val…

This study aims to understand the relationship between urinary function (like bladder control and flow) and the development of other common age-related health problems, such as diabetes, heart disease, and high blood pressure. It will follow 500 Beijing residents aged 60 and olde…