Simple urine test may spot bladder trouble in children
NCT ID NCT07513363
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether three proteins in urine—RhoA, NGF, and BDNF—can help doctors diagnose and monitor overactive bladder in children aged 4 to 18 who also have low vitamin D. Researchers will measure these proteins before and after standard behavioral therapy (urotherapy). The goal is to find a non-invasive way to track the condition without needing catheters or scans.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple urine test to help diagnose and track overactive bladder in children, reducing the need for invasive procedures.
- What could go wrong
- This is a small, early-stage observational study (52 children) that only measures biomarkers. It does not test a new treatment, so even positive results may not change clinical practice immediately.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 52 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
May 2026
An estimate. Start dates often move.
- Expected to finish
-
Jan 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Up to 18 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 4-18 years presenting with active OAB symptoms (frequency, urgency) Exclusion Criteria: * Neurological diseases * Malignancy * Active urinary tract infections * Anatomical bladder anomalies * History of prior OAB treatment/urological surgery.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Overactive bladder are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Marmara University School of Medicine Urology Department
Pendik, Istanbul, 34100, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could vitamin d play a role in sleep apnea severity?
- One vitamin a pill before transplant: a new shield against a deadly complication?
- Could your bone health decide if a dental implant lasts?
- Could vitamin d levels influence asthma control?
- Could vitamin d levels influence cholesterol in obese diabetes patients?
- Diabetes drug class may change how the bladder behaves