OPIOID USE
Clinical trials for OPIOID USE explained in plain language.
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New nerve block aims to cut opioid use after colon surgery
Symptom relief Not yet recruitingThis study looks at whether a special nerve block given during left-sided colon surgery can better control pain and reduce the need for strong painkillers like opioids. About 400 adults having minimally invasive colon surgery will be observed. The goal is to see if this approach …
Matched conditions: OPIOID USE
Sponsor: Antonio Caycedo, MD • Aim: Symptom relief
Last updated May 26, 2026 11:16 UTC
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Mind over matter: simple audio exercises may cut opioid use after broken bones
Symptom relief Not yet recruitingThis study tests whether listening to short, guided mindfulness audio recordings before and after surgery for a broken arm or leg can help reduce pain, anxiety, and the need for opioid painkillers. Fifty adults at Hamilton General Hospital will be randomly assigned to either the …
Matched conditions: OPIOID USE
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated May 26, 2026 11:07 UTC
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Nerve block may cut pain and nausea after Weight-Loss surgery
Symptom relief Not yet recruitingThis study tests whether an extra nerve block during weight-loss surgery can lower pain, nausea, and the need for pain medication in the first three days after surgery. About 200 adults having sleeve gastrectomy or gastric bypass will be randomly assigned to receive either standa…
Matched conditions: OPIOID USE
Phase: NA • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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New study aims to ease chronic pain after breast removal
Symptom relief Not yet recruitingThis study compares two types of nerve blocks (erector spinae block vs. paravertebral block) given before mastectomy to see which one better prevents chronic pain three months after surgery. About 132 adults having a total mastectomy will be randomly assigned to receive one of th…
Matched conditions: OPIOID USE
Phase: NA • Sponsor: American University of Beirut Medical Center • Aim: Symptom relief
Last updated May 19, 2026 11:47 UTC
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New study aims to ease pain after breast surgery without strong drugs
Symptom relief Not yet recruitingThis study compares two types of nerve blocks to see which one provides better pain relief after breast surgery. 54 women will receive one of the blocks before surgery, and their pain and need for painkillers will be tracked for 24 hours. The goal is to find a more effective way …
Matched conditions: OPIOID USE
Phase: NA • Sponsor: Engin Çetin • Aim: Symptom relief
Last updated May 18, 2026 12:02 UTC
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Kratom under the microscope: new study tests safety in former opioid users
Knowledge-focused Not yet recruitingThis study aims to understand how kratom affects people who have used opioids in the past. Researchers will compare kratom with another substance and a placebo to see how it moves through the body and what effects it has. The goal is to learn more about the potential risks and be…
Matched conditions: OPIOID USE
Phase: PHASE1 • Sponsor: Christopher D. Verrico • Aim: Knowledge-focused
Last updated May 26, 2026 11:19 UTC
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Opioid study seeks clues in Body's stress response
Knowledge-focused Not yet recruitingThis study looks at how opioid use affects oxidative stress—a type of body stress linked to many diseases. Researchers will collect blood samples and health information from 120 adults who are already taking opioids as part of their regular care. No new treatments or changes to c…
Matched conditions: OPIOID USE
Sponsor: EPC Education s.r.o. • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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New pill bottle aims to curb opioid overuse after surgery
Knowledge-focused Not yet recruitingThis study tests a specially designed opioid package (called OPP) to see if it helps doctors prescribe fewer pills and patients use them more safely after orthopedic surgery. About 352 adults will receive their pain medication in either the new package or a standard bottle. Resea…
Matched conditions: OPIOID USE
Phase: NA • Sponsor: UConn Health • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC