New study aims to ease chronic pain after breast removal
NCT ID NCT07561411
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two types of nerve blocks given before mastectomy to see which one better prevents chronic pain. About 132 adults having a mastectomy will be randomly assigned to receive either an erector spinae block or a paravertebral block. Researchers will track pain, opioid use, and emotional well-being for 3 months after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 132 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients between 18 and 80 years old. * Scheduled to total mastectomy with or without axillary dissection * Willing to receive regional anesthesia in addition to GA * ASA classification 1-3 Exclusion Criteria: * Previous thoracic surgery with an incision of \>2 cm * Patient's refusal * Allergy to local anesthetics * Pregnant women * Any contraindications to thoracic PVB, including intrathoracic infection, infection at the puncture site, cancer invasion of the puncture site, severe spinal deformity, history of spinal surgery, and severe coagulopathy; anticoagulants intake. * American Society of Anesthesiologists (ASA) classification of 4 or higher, * History of chronic pain or untreated clinical severe depression
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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American University of Beirut Medical Center
RECRUITINGBeirut, Lebanon
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