OCD
Clinical trials for OCD explained in plain language.
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Can continued therapy keep OCD symptoms at bay?
Disease control OngoingThis study offers open/aftercare treatment to adults with obsessive-compulsive disorder (OCD) who have completed an earlier study at Stanford's Rodriguez Lab. Participants receive evidence-based psychotherapy and/or pharmacotherapy from trained professionals. The goal is to see i…
Matched conditions: OCD
Sponsor: Stanford University • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Brain pacemaker trial targets Tough-to-Treat OCD
Disease control OngoingThis study tests a personalized deep brain stimulation (DBS) approach for people with severe obsessive-compulsive disorder (OCD) that hasn't improved with standard treatments. Ten adults will first undergo brain mapping to find the best stimulation targets, then receive a DBS dev…
Matched conditions: OCD
Sponsor: Andrew Moses Lee, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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5-Day brain zaps could lift depression and OCD faster than ever
Symptom relief By invitation onlyThis study tests a new, faster version of a brain stimulation treatment called TMS for people with depression or OCD. Instead of daily sessions for weeks, participants get 10 hours of TMS each day for just 5 days. The goal is to see if this quick approach can improve symptoms and…
Matched conditions: OCD
Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Aug 22, 2026 00:00 UTC
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Could a Parkinson's drug tame OCD?
Symptom relief OngoingThis study tests whether tolcapone, a drug used for Parkinson's disease, can reduce symptoms of obsessive-compulsive disorder (OCD) in adults. About 49 people with moderate to severe OCD will receive either tolcapone or a placebo. The main goal is to see if the drug safely lowers…
Matched conditions: OCD
Phase 2 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Watching the brain and body during OCD triggers: a window into the disorder
Knowledge-focused OngoingResearchers at Baylor College of Medicine are studying how brain activity and visible behaviors, like head movements, facial expressions, and voice tone, change during tasks that trigger OCD symptoms. Adults with OCD and healthy volunteers will complete tasks that provoke distres…
Matched conditions: OCD
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC