OBESITY (DISORDER)

This study looks at whether tirzepatide, a once-weekly injection, is acceptable and helpful for postmenopausal women who have had hormone-positive breast cancer and are now living with obesity. Over 6 months, 30 participants will take the medication, have monthly check-ins, and u…

This study tests whether eating meals at times that match your natural body clock (chrono-nutrition) can help people who have had weight loss surgery keep the weight off and improve their health. About 246 adults who had sleeve gastrectomy at least 6 months ago will either follow…

This study tests whether an AI-driven peer-mentoring program can help healthy 12- to 25-year-olds eat better and move more, preventing obesity and heart disease. Participants will be split into three groups: AI-based mentoring, traditional peer-mentoring, or standard health educa…

This study looks at how obesity and low iron levels change where iron builds up in the body, like in the liver and heart. Researchers will compare people with obesity who have iron deficiency to those who don't, using MRI scans and fat tissue samples. After weight-loss surgery, t…

This study looks at how well tirzepatide, a newer weight-loss medication, works when used in regular doctor visits—not just in strict research settings. Researchers will track weight loss and dosing patterns in 1700 adults with obesity across multiple Dutch clinics over six month…

This study looks at how a less invasive weight-loss procedure called endoscopic sleeve gastroplasty (ESG) affects stomach emptying, hormones, and gut bacteria. Researchers will compare ESG to traditional surgical sleeve gastrectomy in 40 adults with obesity. The goal is to unders…

This study will enroll 20 severely obese adults who are scheduled for weight-loss surgery. Half will use a continuous glucose monitor (CGM) and the other half will use standard finger-prick testing to check their blood sugar. The goal is to see if CGM helps reduce blood sugar swi…

This study looks at whether common chemicals found in plastics, food containers, and pesticides are linked to childhood obesity. Researchers will measure levels of PFAS, bisphenol A, and other chemicals in the blood of 80 children aged 6 to 15, comparing those who are obese with …

This study observes 30 adults in Mexico who are already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans, heart CT scans, and body composition tests to see how the drug affects knee cartilage, heart fat, and overall body health over one y…

This study looks at how obesity and gastroesophageal reflux disease (GERD) are connected. Researchers will measure how common obesity is among 200 adults with GERD. The goal is to better understand the link between these two conditions.

This study will analyze medical records from 400 adults with type 2 diabetes or obesity to see how well semaglutide works over three years for heart, kidney, and metabolic health. Researchers will compare blood sugar control in people taking semaglutide versus other diabetes medi…