NEUROENDOCRINE TUMORS

This study tested a combination of two drugs, pembrolizumab and lenvatinib, in 20 people with advanced neuroendocrine tumors that had worsened despite prior treatments. The goal was to see if the combination could shrink tumors or slow cancer growth. The study measured how many p…

This study tested a treatment called TheraSphere for people with neuroendocrine tumors that have spread to the liver and cannot be removed by surgery. TheraSphere uses tiny radioactive beads delivered directly to the liver to kill cancer cells. The trial included 24 adults who ha…

This study tested a new drug, BXCL701, taken as a pill, together with the immunotherapy pembrolizumab in men with advanced prostate cancer that has stopped responding to hormone therapy. The goal was to find the best dose and see if the combination could shrink tumors or slow the…

This study tested whether adding the oral drug axitinib to the standard treatment sandostatin LAR could slow cancer growth in people with advanced neuroendocrine tumors that started outside the pancreas. 256 adults with tumors that had recently grown were randomly assigned to get…

This early-stage study tested a combination of a radioactive drug (177Lu-DOTA-TATE) and a targeted pill (olaparib) in 18 adults with certain tumors that have a specific marker. The goal was to find the safest dose and understand side effects. This approach aims to make tumor cell…

This study tested a drug called surufatinib in 36 Japanese patients with neuroendocrine tumors that had stopped responding to standard treatments. The goal was to see if the drug could shrink tumors and control the disease. The study was completed and measured side effects and ho…

This study analyzed data from 168 adults with a rare type of digestive neuroendocrine tumor (well-differentiated grade 3). Researchers compared survival and tumor response between patients who received platinum-based chemotherapy as their first treatment and those who received ot…

This study collected information on the EchoTip AcuCore, a needle used to take tissue samples during an endoscopic ultrasound. The goal was to see how often the needle successfully gets a sample without needing a replacement. The study included 183 adults with various tumors or p…

This study follows 20 people who previously received the drug 177Lu-satoreotide tetraxetan for neuroendocrine tumors. The goal is to watch for long-term side effects, including new cancers. No new treatment is given; it is purely a safety follow-up.

This study looked at 116 people with advanced neuroendocrine tumors to see if a gene marker called MGMT could predict which chemotherapy works best. Researchers compared two chemo drugs—alkylating agents and oxaliplatin—based on whether the tumor had a methylated (active) or unme…