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Radiation beads aim to shrink liver tumors in neuroendocrine cancer trial

NCT ID NCT04362436

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This phase II trial tested a treatment called TheraSphere selective internal radiation therapy (SIRT) in 24 patients with neuroendocrine tumors that had spread to the liver and could not be surgically removed. The treatment involves injecting tiny radioactive beads into the liver's blood supply to deliver radiation directly to tumors. The study measured safety, tumor shrinkage, and how long patients lived without their disease getting worse.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Imperial College NHS Trust

    London, W12 0HS, United Kingdom

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TheraSphere (yttrium-90 glass microspheres) for selective internal radiation therapy

What this could lead to

If successful, this could offer a new treatment option for patients with inoperable liver metastases from neuroendocrine tumors, potentially improving tumor control and survival.

What could go wrong

This is a small, early-phase trial with only 24 participants, so results may not apply broadly. Radiation to the liver carries risks of liver damage, fatigue, and other side effects.

Conditions

The condition(s) this trial relates to.

neuroendocrine neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.