Gene test may guide chemo choice for rare tumors
NCT ID NCT03217097
First seen Nov 21, 2025 · Last updated May 19, 2026 · Updated 26 times
Summary
This study looked at 116 people with advanced neuroendocrine tumors to see if a gene marker called MGMT could predict which chemotherapy works best. Researchers compared two chemo drugs—alkylating agents and oxaliplatin—based on whether the tumor had a methylated (active) or unmethylated (inactive) MGMT gene. The goal is to help doctors choose the right treatment for each patient, reducing trial and error.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CH Annecy Genevois
Pringy, 74374, France
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CHU d'Angers
Angers, 49933, France
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Centre Oscar Lambret
Lille, 59020, France
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Hôpital Beaujon - APHP
Clichy, 92118, France
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Hôpital Claude Hurriet - CHRU Lille
Lille, 59037, France
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Hôpital Cochin - APHP
Paris, 75014, France
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Hôpital Edouard Herriot - Hospices Civils de Lyon
Lyon, 69003, France
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Hôpital Estaing, CHU de Clermont-Ferrand
Clermont-Ferrand, 63003, France
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Hôpital François Mitterrand - CHU Dijon Bourgogne
Dijon, 21000, France
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Hôpital Nord - CHU Saint Etienne
Saint-Priest-en-Jarez, 42270, France
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Hôpital Privé Jean Mermoz
Lyon, 69008, France
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Hôpital Rangueil - CHU Toulouse
Toulouse, 31059, France
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Hôpital Robert Debré - CHU Reims
Reims, 51092, France
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Hôpital Saint Louis - APHP
Paris, 75010, France
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Hôpital Sud - CHU Amiens
Amiens, 80054, France
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Hôpital Trousseau - CHU Tours
Tours, 37044, France
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Institut Gustave Roussy
Villejuif, 94805, France
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Institut Paoli Calmettes
Marseille, 13009, France
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Institut de Cancérologie de la Loire
Saint-Priest-en-Jarez, 42270, France
Conditions
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