NEURODEGENERATIVE DISEASES

This study tested an experimental drug called AMX0035 in 139 people with progressive supranuclear palsy (PSP), a rare brain disease that affects movement and thinking. The goal was to see if the drug could slow down the disease. Participants received either the drug or a placebo,…

This study tested an experimental drug called XPro1595 in 208 people with early Alzheimer's who also had signs of brain inflammation. The goal was to see if the drug could improve thinking, memory, and daily function compared to a placebo. Researchers also checked for safety and …

This study looked at the long-term safety of a drug called AOC 1001 in adults with myotonic dystrophy type 1 (DM1), a genetic muscle disease. 37 people who completed an earlier study received multiple doses of the drug by IV. Researchers tracked side effects and measured drug lev…

This study looked at whether a simple, painless ultrasound can help doctors diagnose CANVAS, a rare genetic disorder that causes balance problems, nerve damage, and dizziness. Researchers measured the size of nerves in 35 adults with CANVAS and compared them to healthy people. Th…

This study tested whether a daily NAD+ supplement can improve thinking and reduce inflammation in healthy women aged 40 to 80. Over 4 weeks, participants took either NAD+ or a placebo and completed computer tests and blood draws. The goal was to see if NAD+ affects memory, attent…