NEPHROTIC SYNDROME

This study tests whether adding belimumab to rituximab works better than rituximab alone for people with membranous nephropathy, a kidney disease that causes protein leakage. About 58 adults will receive either the combo or rituximab alone, and researchers will check if their kid…

This study tests a drug called atacicept in 200 adults and teens with several autoimmune kidney diseases, including IgA nephropathy and focal segmental glomerulosclerosis. The goal is to see if it safely reduces protein in the urine and helps preserve kidney function. Participant…

This study tests whether a smartphone app can help doctors and young adults with chronic kidney disease (CKD) follow the latest treatment guidelines. The app provides reminders, education, and care recommendations to delay kidney disease progression. About 80 participants aged 16…

This study tests whether combining two immune-suppressing drugs, rituximab and cyclosporine, can safely reduce protein leakage in the urine of people with membranous nephropathy, a kidney disease where the immune system damages kidney filters. About 30 adults with persistent prot…

This study tests whether a smartphone app can help people with kidney problems control body swelling by guiding daily adjustments of their water pills (diuretics). Thirty participants will use the app for 90 days, entering their weight and blood pressure daily and following the a…

This study looks at whether a protein called PCSK9 is higher in people with nephrotic syndrome (a kidney condition causing protein leakage) and if it relates to kidney damage. Researchers will compare blood and kidney tissue samples from 75 participants—those with the condition a…

This study aims to see if a lab-grown cell system can detect a substance in the blood that causes protein leakage in the urine of people with a kidney condition called nephrotic syndrome. Researchers will compare blood and urine samples from 150 participants, including patients w…

This study aims to learn more about kidney diseases caused by the immune system, such as nephrotic syndrome and lupus nephritis. Researchers will follow up to 2,000 adults and children over 10 years old, collecting medical history, physical exams, and blood or urine samples. The …

This study looks at blood samples from 100 adults with a kidney condition called idiopathic nephrotic syndrome. Researchers want to measure levels of certain autoantibodies (anti-nephrin) to see if they are linked to the disease. The goal is to better understand the disease, not …

This study interviews 150 children, adults, and parents about their experiences with swelling caused by Nephrotic Syndrome. Researchers will use the information to create a survey that helps test new medications. No treatment is given; the goal is to better understand symptoms.