NEOPLASM METASTASIS

This study tested a new treatment for people with pancreatic cancer that spread only to the liver, after their first chemotherapy stopped working. The treatment delivers two chemotherapy drugs directly to the liver through a thin tube, followed by more chemo either through the tu…

This early-phase study tested a new drug called LY3039478 in 247 adults with advanced or metastatic cancer, including lymphoma. The main goals were to find a safe dose and to see how the drug affects the body and tumors. While the study looked for signs of tumor shrinkage, it pri…

This study tested a new immunotherapy drug, ezabenlimab (BI 754091), combined with other cancer medicines in 211 adults with advanced solid tumors that had spread. The goal was to see if the combination could shrink or eliminate tumors. Participants received treatment as long as …

This early-phase study tested a new drug called MRX-2843 in 42 adults with advanced or metastatic solid tumors that had not responded to prior treatments. The main goal was to check the drug's safety and find the best dose. Researchers monitored side effects and how the drug move…

This study observed 500 adults with colorectal cancer that spread to the liver. All were treated with the Emprint Microwave Ablation System, which uses heat to destroy tumors. The goal was to see how well the system controls tumors locally over 12 months and to track any side eff…

This study explored whether people with intestinal polyps have cancer cells or specific proteins in their blood that could signal early tumor spread. Researchers compared blood samples from 120 patients undergoing colonoscopy—some with polyps, some without. The goal was to find n…

This study observed 152 adults with colorectal cancer that spread to the liver. Doctors used tiny beads called LifePearl Microspheres loaded with chemotherapy to treat the liver tumors. The goal was to see how and when doctors choose this treatment, and to track safety and surviv…

This study looked at how patients with advanced cancer respond to being offered a chance to discuss and write down their wishes for end-of-life care. Researchers followed 71 patients to see who took up the offer and how it affected their care. The goal is to improve how doctors a…

This study analyzed data from over 19,000 liver cancer patients to see if the risk of cancer spreading (metastasis) differs between men and women. Researchers used machine learning to create separate prediction models for each sex. The goal was to improve early detection and pers…

This study looked at whether analyzing the DNA of tumors from people with advanced cancer could help doctors pick a targeted treatment. About 550 adults with cancer that had spread took part. The goal was to see how often this approach could find a DNA change that matched an avai…