Myocardial infarction (MI)

Researchers compare two timing strategies for the Impella CP heart pump in people who have a heart attack and develop cardiogenic shock, a dangerous state where the heart cannot pump enough blood. One group receives the pump before the artery-opening procedure called PCI, while t…

This study tests a community-based exercise program for people aged 50 and older who have at least two chronic conditions, such as heart disease, diabetes, arthritis, or obesity. The program is designed to improve muscle strength, heart and lung fitness, and overall well-being. R…

This trial is testing the best timing for opening additional blocked arteries in people who have had a severe type of heart attack (STEMI) with multiple blocked vessels. After the main blocked artery is opened, participants are randomly assigned to have the other blockages treate…

This study tests whether a 6-month program delivered through the Telegram messaging app can help people stop smoking after a heart attack. 142 adult smokers who use Telegram will either get the chatbot support or standard advice. The goal is to see if more people quit with the ch…

This trial tests whether adding eccentric cycling—a type of exercise where muscles lengthen under tension—to standard cardiac rehabilitation can improve recovery in people who have had a heart attack. Eccentric exercise may allow higher muscle loads with less cardiovascular deman…

This study tests whether a short course of the antibiotic rifaximin can improve how well the blood thinner ticagrelor works in people who have had a heart attack. The idea is that unhealthy gut bacteria may interfere with the drug, and clearing them out could help prevent future …

This study tests whether digital health tools can help people recover safely at home after a heart attack. Researchers will compare two types of follow-up care: education alone versus education plus extra support like symptom tracking and virtual appointments. The goal is to redu…

This trial tests whether a smartphone app called Antshrike, paired with a smartwatch, can predict heart attacks or strokes within 3-4 days in people at high risk. Participants aged 40 to 79 with existing heart disease or elevated risk will wear the smartwatch for 18 months while …

This study looks at whether 12 virtual health coaching sessions over 16 weeks can help people with heart disease (like heart failure or a heart attack) improve their health, reduce stress, and lower the chance of going back to the hospital. About 70 adults will take part, and the…

This study investigates clonal hematopoiesis, an age-related condition where blood stem cells acquire mutations, and how it triggers inflammation linked to heart disease. Researchers will compare immune cells from healthy people, those with high-risk mutations, and patients with …

This study will follow 400 people who had a heart attack and have moderately reduced heart function (ejection fraction 35-50%). Participants will get a small implantable heart monitor to track their heart rhythm for up to 5 years. The goal is to identify markers that could predic…

This study aims to see if wearable foot-pods (like Stryd) and breathing frequency monitors can accurately measure exercise intensity in people who have had a heart attack in the past 6 months. 24 participants will perform walking tests on flat ground and a treadmill while their o…

This study will develop a new AI-powered model to predict major heart problems after a heart attack. Researchers will analyze data from over 1,500 patients who had a heart attack and received a stent. The goal is to create a more accurate tool than current methods to identify pat…