MYELOMA MULTIPLE

This early-stage trial tests a new daily pill, KTX-1001, for people with multiple myeloma that has returned or stopped responding to other treatments. The study aims to find a safe dose and see if the drug can shrink tumors or slow the cancer. About 125 adults who have tried at l…

This early-stage trial tests a new gene therapy called KLN-1010 for people with multiple myeloma that has come back or not responded to treatment. The therapy works by giving a single injection that instructs the body's own immune cells to become cancer-fighting cells (CAR-T cell…

This study looks at whether people with multiple myeloma who have responded very well to the drug teclistamab can safely stop taking it for a while. Instead of staying on the drug forever, participants who have done well after 6-9 months will pause treatment and restart only if s…

This study tests whether a combination of two drugs (belantamab mafodotin and lenalidomide) given after a stem cell transplant can turn residual myeloma cells undetectable in patients with newly diagnosed multiple myeloma. About 94 adults who have already had a transplant will re…

This study tests two programs designed to help people recently diagnosed with chronic cancer manage their emotions. About 30 participants will try either a guided self-help program or a combined group and self-help program. The main goal is to see if these programs are practical …

This study looks at whether people with multiple myeloma can safely give themselves a standard chemotherapy injection (bortezomib) at home, instead of always going to the hospital. About 100 adults who are stable on treatment and have already had several injections in the clinic …

This study tests whether a connected scale can help monitor people with lymphoma or multiple myeloma who are receiving chemotherapy. Thirty participants will weigh themselves daily at home for about 7 weeks. The medical team will receive alerts if weight or heart rate changes abn…

This study looks at information already collected from 600 people with multiple myeloma. Researchers will combine genetic, clinical, and imaging data to train artificial intelligence models. The goal is to find patterns that could help predict how the disease will progress and ho…

This study is a long-term observation of 1,000 patients receiving stem cell transplants for blood diseases at a hospital on the Qinghai-Tibet Plateau. Researchers will collect information on patient health, treatment results, and costs to understand how high altitude affects reco…

This study is collecting blood, bone marrow, and tissue samples from over 1,000 people with blood cancers like leukemia and myeloma. Researchers will use advanced lab techniques to find unique markers (biomarkers) in each person's cancer. The goal is to better understand these di…

This study collects medical and genetic information from 520 people with multiple myeloma to better understand why the disease progresses or comes back. Researchers will analyze DNA and RNA from patient samples to find patterns linked to treatment response. The goal is to create …