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Gene therapy builds Cancer-Killing cells inside you – no lab needed

NCT ID NCT07075185

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 32 times

Summary

This early-stage trial tests a new gene therapy called KLN-1010 for people with multiple myeloma that has come back or stopped responding to treatment. Instead of removing cells and engineering them in a lab, this therapy works inside the body to create special immune cells that target and attack the cancer. The study will enroll about 70 participants to check safety and find the right dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Peter MacCallum Cancer Centre

    RECRUITING

    Melbourne, Victoria, 3000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Providence Portland Medical Center

    RECRUITING

    Portland, Oregon, 97213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Alfred Paula Fox Melanoma and Cancer Centre

    RECRUITING

    Melbourne, Victoria, 3004, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Royal Prince Alfred

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Blood Protein Disorders disease hematologic disorder immune system disorder immunoproliferative disorder lymphoproliferative syndrome monoclonal gammopathy monoclonal paraproteinemia disease neoplasm Neoplasms by Histologic Type plasma cell myeloma vascular disorder vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.