MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Clinical trials for MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM explained in plain language.
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New transplant timing strategy may tame High-Risk blood cancers
Disease control OngoingThis study tests a specific schedule of chemotherapy drugs (busulfan and fludarabine) followed by a donor stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. After the transplant, a drug called cyclophosphamide is given to help prevent the don…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 09:03 UTC
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New drug combo targets tough leukemia in early trial
Disease control OngoingThis early-phase study tests a new targeted therapy called PVEK, which delivers chemotherapy directly to cancer cells, combined with a standard chemo regimen (FLAG-Ida) for adults with newly diagnosed high-risk acute myeloid leukemia (AML) and other aggressive blood cancers. The …
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 26, 2026 09:00 UTC
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Promising combo targets Hard-to-Treat leukemia
Disease control OngoingThis study tests two drugs together for people with chronic myelomonocytic leukemia (CMML), a rare blood cancer. One drug is a targeted therapy that seeks out and kills cancer cells, while the other is a standard chemotherapy. The goal is to find the best dose and see if the comb…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:35 UTC
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Could a targeted drug boost chemo for tough blood cancers?
Disease control OngoingThis study tested whether adding the drug veliparib to standard chemotherapy helps people with advanced blood cancers like acute myeloid leukemia (AML) and chronic myelomonocytic leukemia (CMML). About 25 adults took part. The goal was to see if the combination improved response …
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New combo pill aims to beat back rare bone marrow cancers
Disease control OngoingThis phase 2 trial tests whether adding venetoclax to the drug ASTX727 works better than ASTX727 alone for people with chronic myelomonocytic leukemia or related bone marrow cancers with too many immature cells. About 132 adults will receive either the combination or ASTX727 alon…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 19, 2026 11:46 UTC
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Donor vaccine could shield transplant patients from dangerous virus
Prevention OngoingThis early-phase trial tests whether giving a CMV vaccine to stem cell donors can boost the recipient's immunity after transplant. About 34 blood cancer patients receiving donor stem cells are involved. The goal is to prevent CMV viremia, a common and serious viral infection, wit…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Prevention
Last updated May 26, 2026 09:03 UTC
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Blood test study seeks hidden enzyme defect in cancer patients
Knowledge-focused OngoingThis study looks at how common acquired pyruvate kinase deficiency is in people with certain blood cancers or pre-cancer conditions. Researchers will take a single blood sample from 100 participants to check for low enzyme activity or gene changes. The goal is to better understan…
Matched conditions: MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 18, 2026 12:03 UTC