New transplant recipe may tame Graft-Versus-Host disease in blood cancer patients
NCT ID NCT02861417
First seen Feb 19, 2026 · Last updated Jun 13, 2026 · Updated 16 times
Summary
This study tests a specific timing of chemotherapy drugs (busulfan and fludarabine) before a donor stem cell transplant, followed by cyclophosphamide after the transplant, to treat high-risk blood cancers like leukemia and lymphoma. The goal is to reduce the chance of the transplant attacking the patient's body (graft-versus-host disease) while still killing cancer cells. About 204 participants will be enrolled to see if this approach lowers the risk of death from non-relapse causes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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