MULTIPLE SYSTEM ATROPHY

This study tests a new treatment for Multiple System Atrophy (MSA), a rare and deadly brain disease. Researchers are giving patients their own stem cells through a spinal tap to see if it can slow the disease. The trial involves 71 adults aged 30-70 who can still walk without hel…

This study tests a new medicine called exidavnemab in people with mild to moderate Parkinson's disease or multiple system atrophy. The goal is to see if it is safe and how the body processes it. Participants continue their usual Parkinson's medications during the trial.

This phase 3 trial tests an experimental drug called amlenetug in 401 people with multiple system atrophy (MSA), a rare and rapidly worsening brain disorder. The study aims to see if the drug can slow the disease's progression and improve survival. Participants receive either the…

This study tests an experimental drug called Lu AF82422 in 64 people with multiple system atrophy (MSA), a rare and serious brain disorder. The goal is to see if the drug can slow down the disease's progression compared to a placebo. Participants receive either the drug or a plac…

This early-stage study tests whether a gene therapy called AAV2-GDNF is safe for people with multiple system atrophy (MSA), a rare and serious brain disorder. Nine adults aged 35-75 with MSA will receive either the gene therapy or a placebo. The main goal is to check for side eff…

This study looks at whether online support groups and remote doctor visits can improve quality of life for people with Parkinson's disease, Lewy body dementia, and similar conditions, as well as their caregivers. About 632 patients and their care partners are taking part. The goa…

This study aims to improve how doctors test for autonomic failure, a condition where the body's automatic functions like blood pressure control don't work properly. About 89 adults with Parkinson's disease, multiple system atrophy, or related conditions will undergo a series of t…

This study looks at how the body's automatic nervous system controls blood flow in the veins of the abdomen, and how this might contribute to high blood pressure in people with a rare condition called Multiple System Atrophy. About 16 participants will undergo tests to measure ve…

This study follows 90 people with Multiple System Atrophy (MSA) in China and Europe to track how the disease progresses over 12 months. Researchers will use regular check-ups, brain scans, and blood tests to measure changes. The goal is to better understand MSA and improve future…

This study follows 150 people with early Parkinson's disease or Multiple System Atrophy (a related condition) for up to 18 months. Researchers measure symptoms and biological markers to understand how these diseases progress. The goal is to gather information that will help desig…

This study enrolls 500 adults with REM sleep behavior disorder (RBD) and healthy volunteers to track early signs of brain diseases like Parkinson's and Lewy body dementia. Participants undergo tests of thinking, movement, smell, and vision. The goal is to prepare for future clini…