MILD TRAUMATIC BRAIN INJURY

This study is testing a new device called TES HT100 that can check for brain injuries in just 5 minutes. It is for adults who come to the emergency room with mild head trauma or certain neurological symptoms like dizziness or confusion. The goal is to see if the device works as w…

This early study tests a device called intermittent theta burst stimulation (iTBS), which uses magnetic pulses to activate brain cells. Researchers want to see if it can safely reduce impulsivity and suicidal thoughts in 55 veterans who have had a mild traumatic brain injury. The…

This study tests whether a breathing technique called heart rate variability biofeedback can ease persistent symptoms after a mild traumatic brain injury (concussion). The trial will include 148 veterans who have had a concussion more than a year ago and still struggle with sympt…

This study tests whether a mobile app can help adults with dizziness after a mild traumatic brain injury. 68 participants will either do standard home exercises or use a gamified app version. The goal is to see if the app leads to greater improvement in dizziness and balance afte…

This study tests a new approach for treating depression in people who have had a mild traumatic brain injury (concussion). Participants will receive a personalized cognitive training program combined with either real or sham brain stimulation over 4 weeks. The goal is to see if t…

This study tests a safe, non-invasive brain stimulation technique (tDCS) that people can use at home while doing computer-based attention exercises. The goal is to see if it can improve complex attention in 160 active-duty service members and veterans who had a mild traumatic bra…

This study tests whether combining a gentle brain stimulation technique called tDCS with computer-based cognitive training can improve thinking and memory in people still having symptoms 3 to 12 months after a mild concussion. Thirty adults will receive 10 sessions over about 3 w…

This study is testing whether cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and daily function in 15 people with mild traumatic brain injury (mTBI) who have trouble sleeping. Participants will learn techniques like sleep scheduling and changing unhelpful tho…

This study tests whether daily symptom tracking via smartphone can help teens with concussion get quicker access to specialty care. About 210 teens aged 13-18 who visit the emergency department with a concussion and are at high risk for long-term symptoms will report their sympto…

This study tests whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can reduce chronic headaches and improve recovery in people with mild traumatic brain injury. Researchers will compare active rTMS to a sham (fake) treatment …

This study tests two types of repetitive transcranial magnetic stimulation (rTMS) to see if they can safely reduce depression symptoms in 198 U.S. military service members and veterans who have had a concussion or mild traumatic brain injury. Participants receive magnetic pulses …

This study tests two different therapies to help people with ongoing memory problems after a concussion. One is traditional cognitive rehabilitation, and the other is a new cognitive-behavioral therapy (CBT) approach. Researchers want to see which one works better for improving h…

This study is testing whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can improve movement and thinking problems in children aged 10-15 who have had a mild traumatic brain injury (concussion). The researchers will use brain…

This study tests special listening exercises designed to help people with mild traumatic brain injury (mTBI) hear more clearly, especially in noisy environments. Researchers will enroll 80 adults aged 18-55 with a history of mTBI. Participants will undergo targeted auditory train…

This study compares two types of talk therapy for insomnia in 160 active-duty military members who have had a mild traumatic brain injury and still have symptoms like trouble sleeping, thinking, or mood issues. One therapy is longer (6 sessions) and the other is shorter (4 sessio…

This study compares two remote training programs to see which better helps people with mild traumatic brain injury (concussion) improve their emotional health and well-being. It involves 300 adults who are at least 6 months post-injury and have trouble identifying or managing emo…

This study aims to see if a new, low-risk therapy called passive neurosensory reintegration training (PNRT) can help reduce dizziness and other symptoms in people with mild traumatic brain injury (mTBI). Researchers will enroll 80 adults with mTBI to test the therapy's safety and…

This study looks at whether adding morning bright light therapy to cognitive training can improve thinking, daily function, and sleep in 144 veterans who have both mild traumatic brain injury and PTSD. Participants will receive either the light therapy or a placebo light device. …

This study tests a noninvasive, personalized brain stimulation treatment called TMS for people aged 18-65 with chronic symptoms after a concussion, such as headache, dizziness, brain fog, or anxiety. Participants will have a 66% chance of receiving active TMS and a 33% chance of …

This pilot study tests a new program called CRISP to help young adults aged 18-29 recover from concussion and manage headaches. The program focuses on support and recovery strategies. Researchers will measure how acceptable the treatment is and track changes in headache severity …

This study looks at whether daily growth hormone shots for 6 months can improve quality of life in veterans who have both mild traumatic brain injury and adult growth hormone deficiency. About 172 veterans aged 21-55 will receive either the hormone or a placebo. The main goal is …

This study tests a new, non-invasive brain stimulation technique called LIP-tES neurofeedback to help reduce light sensitivity in Veterans who have had a mild traumatic brain injury. The goal is to see if the treatment is practical and well-liked by participants. Researchers will…

This study explores whether mild electrical stimulation of a nerve in the forehead can boost the brain's natural waste-clearing system. Researchers will measure changes in blood flow and cerebrospinal fluid movement in 55 healthy adults and people with mild traumatic brain injury…

This study looks at whether mild traumatic brain injuries (mTBIs) in Veterans increase the risk of dementia. Researchers will measure memory, brain waves, brain structure, and certain proteins linked to brain injury and dementia. The goal is to better understand how mTBI may cont…

This study uses powerful MRI scanners to look at the brains and spinal cords of 700 people, including healthy volunteers and those with conditions like multiple sclerosis, Alzheimer's, and Parkinson's. The goal is to understand why some brains stay healthy while others decline. R…

This study is testing whether a non-invasive brain stimulation technique called iTBS, combined with computer-based attention training, can improve focus and daily functioning in people with persistent attention problems after a mild traumatic brain injury (mTBI), with or without …

This study follows 250 adults aged 65 and older who have had a mild traumatic brain injury (TBI), often from a fall. Researchers will check their thinking, physical abilities, mood, and sleep at 2 weeks, 3 months, 6 months, and 1 year after the injury. The goal is to understand h…

This study looks at whether a history of mild traumatic brain injury (like a concussion) is linked to biological changes in people with mild memory problems. Researchers will use a gentle brain stimulation technique and blood tests to explore this connection. The study involves 7…