METASTATIC PANCREATIC CANCER

This study tests a new treatment called Saltikva, made from a weakened salmonella bacteria that carries a human immune-boosting gene. It is given by mouth along with standard chemotherapy to people with metastatic pancreatic cancer that cannot be removed by surgery. The goal is t…

This study tests a two-drug chemotherapy plan (alternating FOLFOX and FOLFIRI) in adults aged 65 and older with newly diagnosed metastatic pancreatic cancer. The goal is to see if this approach causes fewer side effects than the standard three-drug regimen, while still controllin…

This study looks at how safe and effective glipizide, a standard diabetes drug, is for lowering blood sugar in people with pancreatic cancer. About 29 adults with active pancreatic cancer and high blood sugar will take glipizide and have their glucose levels monitored. The goal i…

This study tests whether adding zolbetuximab (a drug that targets a protein called CLDN18.2 found in many pancreatic tumors) to standard chemotherapy helps people with metastatic pancreatic cancer live longer. About 393 adults whose cancer has spread and has the CLDN18.2 marker w…

This early-stage trial tests a new drug called OMO-103, given together with standard chemotherapy, in 26 people with advanced pancreatic cancer that has spread. The main goals are to check the safety of the combination and see if it helps shrink tumors. Participants must not have…

This study tests a new device that places tiny alpha radiation seeds directly into pancreatic tumors. It includes 37 adults with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if the procedure is safe and possible, and to check early signs of tum…

This study was designed to test a new drug called GFH375 in people with advanced pancreatic cancer that has a specific genetic change (KRAS G12D). The goal was to see if the drug could shrink tumors or slow the disease. However, the trial was withdrawn before any participants wer…

This study tests a combination of two drugs, atezolizumab and cabozantinib, in 30 people with advanced pancreatic cancer that has stopped responding to standard treatments. The goal is to see if the combo can shrink tumors or slow the disease. Researchers will also monitor side e…

This study tests a drug called ceralasertib, either alone or combined with olaparib or durvalumab, in people with advanced solid tumors like kidney, bladder, pancreatic, endometrial, and prostate cancers. The goal is to see if these combinations can shrink tumors or slow their gr…

This study was designed to test a new type of PET scan that uses two special substances to find cancer cells with a marker called CA19-9. It was planned for people with pancreatic, bladder, or gastrointestinal cancers. However, the study was withdrawn before any participants were…

This study tests whether taking pancreatic enzyme pills (pancrelipase) can help people with metastatic pancreatic cancer maintain or gain weight. The study includes 17 participants who are starting chemotherapy. Researchers will compare two different dosing schedules and measure …

This study aimed to see if a food supplement called ARACOMPLEX could help maintain quality of life in patients with advanced or metastatic pancreatic cancer who are receiving chemotherapy. The supplement contains maca extract, vitamins, and minerals. The study was withdrawn befor…