METASTATIC PANCREATIC CANCER

This study is testing a modified schedule of two standard chemotherapy combinations (FOLFOX and FOLFIRI) for older adults (65+) with newly diagnosed, advanced pancreatic cancer that has spread. The main goal is to see if alternating these treatments every two weeks is easier for …

This study is testing whether a combination of two drugs, atezolizumab and cabozantinib, can help control advanced pancreatic cancer that has spread and stopped responding to standard chemotherapy. It will involve about 30 patients to see if the treatment is safe and if it can sh…

This study is testing how well and safely the diabetes medication glipizide works to lower high blood sugar in people with pancreatic cancer. Researchers are enrolling about 29 participants with active pancreatic cancer and high blood sugar to measure their glucose levels before …

This study is testing a new way to treat advanced pancreatic cancer by placing tiny radioactive seeds directly into the tumor. The seeds release a powerful form of radiation called alpha radiation, which is designed to destroy cancer cells from the inside. Researchers are checkin…

This early-stage study is testing the safety and initial effects of an experimental drug called OMO-103 when given alongside standard chemotherapy (gemcitabine/nab-paclitaxel) to patients with newly diagnosed metastatic pancreatic cancer. The main goal is to find a safe dose and …

This study is testing if adding a new drug called zolbetuximab to standard chemotherapy helps people with advanced pancreatic cancer that has spread. The drug works by targeting a specific protein found on many pancreatic cancer cells, aiming to help the immune system attack the …

This study aimed to test an experimental drug called GFH375 in people with advanced pancreatic cancer that had spread and had a specific genetic change (KRAS G12D mutation), and who had already tried other treatments. The goal was to see if the drug could shrink tumors, control t…

This study aimed to test a new two-step PET scan method to better find cancer cells that produce a specific marker called CA19-9. It was designed for adults with certain cancers like pancreatic, bladder, or gastrointestinal tumors. The main goals were to find the safest dose and …

This study is testing whether pancreatic enzyme replacement therapy (PERT) can help people with advanced pancreatic cancer maintain their body weight while on chemotherapy. Researchers are comparing two different dosing schedules of the enzyme supplement pancrelipase. The main go…

This study aimed to see if a specific nutritional supplement could improve the quality of life for people with advanced pancreatic cancer. It planned to compare the supplement against a placebo in patients receiving chemotherapy. The trial was withdrawn before any participants we…