METASTATIC LUNG CANCER

This is the first study in people to test a new drug called BBO-8520 for advanced non-small cell lung cancer that has a specific genetic change called KRAS G12C. The main goals are to find a safe dose and see if the drug can help shrink tumors. The study will test BBO-8520 alone …

This study is testing a new oral drug, S241656, alone and in combination with other cancer therapies. It aims to find a safe and effective dose for adults with advanced cancers, including lung, pancreatic, and colorectal cancers, that have specific genetic mutations like KRAS or …

This study is testing a new type of personalized cell therapy called OBX-115 in adults with advanced melanoma or non-small cell lung cancer that has progressed after standard treatments. Doctors take a patient's own immune cells from a tumor, genetically engineer them to be more …

This is the first human study testing a new drug called IPH5301 for people with advanced cancers that have spread. The trial has two parts: first finding the safest dose of IPH5301 alone, then testing it combined with standard chemotherapy in breast cancer patients. It's for adul…

This is the first human study testing a new experimental drug called BBO-10203 in people with advanced solid tumors that have spread or cannot be removed by surgery. The main goal is to find safe doses and see how the body processes the drug, both alone and when combined with oth…

This study aims to learn about people who have lived for more than three years after being diagnosed with advanced, spreading lung cancer and are no longer on standard chemotherapy. Researchers will follow 1,000 such patients to understand their health status, quality of life, an…

This study aims to see if simple blood tests can predict how well immunotherapy will work for people with advanced lung cancer. Researchers will track 300 patients receiving first-line immunotherapy, taking regular blood samples to look for cancer DNA and immune cell changes. The…

This study aims to understand the memory, mood, and thinking problems that some patients experience while taking targeted oral drugs for a specific type of lung cancer. Researchers will work closely with 20 patients who have reported these side effects to describe their experienc…

This study aims to collect long-term health information and blood/tissue samples from 730 lung cancer patients treated at Nantes University Hospital. By tracking patients from diagnosis through their entire treatment journey, researchers hope to understand how treatments work in …