METASTATIC LUNG CANCER

This study tests an experimental treatment called OBX-115 for people with advanced melanoma or non-small cell lung cancer that has spread or stopped responding to standard therapies. OBX-115 uses a patient's own tumor-fighting immune cells (TILs) that have been modified to produc…

This early-stage study tests a new drug called BBO-8520 in people with advanced non-small cell lung cancer that has a specific genetic change (KRAS G12C). The main goals are to check the drug's safety and see if it can shrink tumors. About 350 adults will take part, and the drug …

This early-phase study tests a new drug called BBO-10203 in about 392 adults with advanced solid tumors (like breast, lung, or colorectal cancer) that have not responded to other treatments. The drug works by blocking a key cancer growth pathway. The main goals are to find the sa…

This early-stage study tests an oral drug called S241656 in adults with advanced cancers that have certain gene changes (KRAS, BRAF, or related mutations). The drug is given alone or with other cancer treatments. The goal is to find safe doses and see if the drug shrinks tumors. …

This early-phase study tests a new drug called IPH5301 in people with advanced solid tumors that have spread. The drug aims to block a protein (CD73) that helps tumors hide from the immune system. The trial first finds the safest dose alone, then tests it with chemotherapy and an…

This study looks at memory, thinking, and mood problems that can happen with certain targeted drugs for lung cancer. Researchers will work with 20 patients to better understand these side effects and how they affect daily life. The goal is to create a care plan that helps patient…

This study looks at people with metastatic lung cancer who have lived for at least three years after diagnosis and are no longer on chemotherapy. Researchers want to learn about their health, daily life, and any challenges they face. Participants will fill out questionnaires abou…

This study is collecting health information and biological samples from 730 adults newly diagnosed with lung cancer. Researchers aim to track how patients respond to treatments in real-world settings, including those often excluded from clinical trials. The goal is to better unde…

This study is testing whether a liquid biopsy (a simple blood test) can predict how well first-line immunotherapy works in people with advanced non-small cell lung cancer. Researchers will track genetic changes in the blood before and during treatment to see if they match tumor s…