Medulloblastoma

This study looks at a new way to give radiation to children with brain tumors that need whole-brain and whole-spine treatment. The technique, called vertebral body-sparing proton therapy, aims to protect the front of the spine bones to preserve bone marrow and growth. Researchers…

This phase 3 trial compares two standard chemotherapy regimens for children under 5 with a low-risk type of medulloblastoma. The main goal is to see which approach better protects thinking and learning skills 2.5 years after diagnosis. The study will also track survival and side …

This study is developing an artificial intelligence (AI) system that can analyze standard MRI brain scans to determine the specific molecular subtype of a child's brain tumor before surgery. The research includes 1,400 children under 18 with suspected brain tumors, using both pas…

This study investigates the most aggressive form of medulloblastoma, a common childhood brain tumor, focusing on tumors with high MYC gene activity. Researchers will analyze tumor tissue collected during standard surgery and grow 3D tumor models in the lab to understand how MYC d…

This study tests a lab technique called pharmacoscopy that analyzes a patient's tumor tissue to find which drugs might work best for them. It includes 40 adults with various aggressive or rare brain tumors that have not responded to standard treatments. The main goal is to see if…

This study is testing a mobile app called my.naviGATE for teens and young adults (ages 15-24) who have finished cancer treatment. The app provides personalized education, peer support, and tracks how patients are doing. Researchers want to see if the app helps patients feel more …