MEDULLOBLASTOMA
Clinical trials for MEDULLOBLASTOMA explained in plain language.
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Intense chemo battle for Babies' brains: which drug combo wins?
Disease control CompletedThis study aimed to find the best chemotherapy treatment for very young children (under 3 years old) with newly diagnosed, high-risk brain tumors. Researchers compared two intense drug combinations—one with a drug called methotrexate and one without—to see which was more effectiv…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Apr 04, 2026 01:36 UTC
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New radiation approach tested for Kids' brain cancer
Disease control CompletedThis completed Phase 3 trial compared two different radiation schedules for treating standard-risk medulloblastoma, a type of brain tumor, in children and young adults aged 4-21. All 52 participants received the same chemotherapy, but were randomly assigned to receive either stan…
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE3 • Sponsor: Institut Curie • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Scientists test Direct-to-Brain immune therapy in kids with aggressive tumors
Disease control CompletedThis early-phase study tested a personalized cell therapy for children and young adults with recurrent or hard-to-treat brain tumors. Doctors collected patients' own immune cells, engineered them in a lab to target a specific protein (EGFR) on the tumor, and then delivered these …
Matched conditions: MEDULLOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Scientists track Radiation's hidden toll on young brains
Knowledge-focused CompletedThis study aimed to understand the side effects of radiation therapy on children and young adults with brain tumors. Researchers followed 76 participants under age 21 for up to 5 years, using blood tests, brain scans, and thinking skill assessments. The goal was to learn how radi…
Matched conditions: MEDULLOBLASTOMA
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Scientists seek clues in fight against rare brain cancers
Knowledge-focused CompletedThis study aimed to gather information to better understand rare brain and spine tumors. Researchers collected health surveys and saliva samples from 326 adult participants who had been diagnosed with one of these rare cancers. The goal was to learn about risk factors, treatment …
Matched conditions: MEDULLOBLASTOMA
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists test DNA blueprint method to find better treatments for kids with tough cancers
Knowledge-focused CompletedThis study tested whether doctors could quickly analyze the genetic makeup of a child's tumor and use that information to choose a personalized treatment plan. It involved 186 children and young adults (up to age 21) whose cancers had returned or did not respond to standard treat…
Matched conditions: MEDULLOBLASTOMA
Phase: NA • Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC