Male infertility

This study looks at how surgery to fix varicocele—enlarged veins in the scrotum—affects the number of immature sperm cells in semen. Infertile men aged 20 to 45 with varicocele will have a microsurgical procedure to tie off the abnormal veins. Their semen will be tested before su…

This study tests a more thorough varicocele surgery that strips away extra veins, compared to the standard method. About 160 infertile men with varicocele will be randomly assigned to one of the two procedures. The goal is to see if the extended stripping reduces the chance of va…

This study looks at whether damage to sperm DNA (called sperm DNA fragmentation) is common in men undergoing fertility treatment and whether it affects the chance of a live birth. About 800 men will provide semen and blood samples. Those with high sperm DNA damage (above 20%) wil…

This study tests two different calcium treatments (ionophores) to help eggs fertilize during IVF when previous attempts failed. Researchers will compare which treatment works better and check embryo health. The study involves 20 couples with a history of low fertilization.

This study looks at 40 infertile men with varicoceles (enlarged veins in the scrotum) to see if blood flow measurements in the testicles can predict how well they will respond to surgery. Participants will have ultrasound and blood tests before and three months after a standard m…

This pilot study will follow 90 men aged 18-50 who need heart surgery, some of whom will take the blood thinner warfarin afterward. Researchers will track changes in sperm count, movement, shape, DNA health, and hormone levels over 12 months. The goal is to see if warfarin harms …