Male infertility

This study tests a new device that sorts sperm without spinning them, which may reduce DNA damage often seen in older men. It involves 378 couples where the male partner is 40 or older and the female partner has at least 5 mature eggs. The goal is to see if this device leads to m…

This study tests whether taking royal jelly, a bee product, can improve sperm DNA quality and pregnancy rates in couples with unexplained infertility. Eighty men will take either royal jelly or a placebo daily for three months. Researchers will measure sperm damage, hormone level…

This study tests whether a single midline incision in the pubic area works as well as the standard two incisions (one on each side) for repairing varicoceles in both testicles. The trial enrolls men aged 18 to 45 with a palpable bilateral varicocele and infertility lasting at lea…

This study looks at whether drinking a daily serving of gazpacho, a cold tomato-based soup, can improve semen quality in men with low sperm counts or poor sperm movement. Eighty men will follow a Mediterranean diet for 12 weeks, with half also drinking gazpacho each day. Research…

This study compares two IVF methods for couples where the male partner has severe sperm shape issues (teratospermia). One group gets standard ICSI (sperm injected into egg), the other gets ICSI plus a chemical boost to activate the egg. The goal is to see which leads to more live…

This study tests whether taking probiotics daily for about 100 days can improve sperm count, movement, and shape in men with infertility. Sixty men aged 20 to 45 will be randomly assigned to receive either probiotics or a placebo. Researchers will measure sperm quality at the sta…

This Stanford study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help produce sperm. Ten men with nonobstructive azoospermia who previously failed sperm retrieval will receive the injection. Three months later, doctors will check for sperm…

This study tests a new lab technique called HyperSperm to see if it can make sperm move better and stay healthy. Researchers will collect semen samples from 300 men with different fertility issues and compare the new method to the standard one. The goal is to find a safer and mor…

This study looks at whether levels of a sperm protein called PLCZeta are linked to semen quality and fertility outcomes. Researchers will measure PLCZeta in sperm samples from couples undergoing IVF or routine semen analysis. The goal is to see if low or abnormal PLCZeta predicts…

This study is developing an artificial intelligence (AI) platform to analyze sperm samples and predict how likely they are to lead to a successful pregnancy during IVF. Researchers will collect and study 500 semen samples from men undergoing IVF, using AI to look for patterns tha…

This study is creating a biobank of male biological samples, such as sperm and testicular tissue, from men undergoing fertility treatments. The goal is to collect and store these samples for future research on male infertility and assisted reproductive technologies. Up to 1,000 p…