MALARIA

This study tested a new vaccine designed to stop the malaria parasite from spreading from mosquitoes to people. It involved 105 healthy adults aged 18 to 50 who received three shots over a few months. The main goal was to check safety and how the immune system responded, not to t…

This early-stage trial tested an experimental RNA-based malaria vaccine in 60 healthy adults. The goal was to check if the vaccine is safe and triggers an immune response. Researchers gave three different dose levels to find the best one for future studies.

This study tested two experimental malaria vaccines in 345 healthy Indonesian soldiers deployed to a malaria-prone region. The goal was to see if the vaccines are safe and can prevent natural malaria infection. Participants received either a vaccine or a placebo, and researchers …

This study tested an experimental RNA-based vaccine (BNT165e) designed to prevent malaria caused by the P. falciparum parasite. 163 healthy adults who had never had malaria received the vaccine, and researchers checked for side effects, immune response, and whether the vaccine co…

This study tested the safety and immune response of the R21/Matrix-M malaria vaccine in 122 African children aged 5-36 months, both with and without HIV. The goal was to see if the vaccine is safe and triggers a strong immune response in children living with HIV. Results will hel…

This study tested a new malaria vaccine called R21/Matrix-M in 594 children aged 5 to 36 months in Mali. The goal was to see if the vaccine is safe and triggers a strong immune response, both when given alone and alongside routine childhood vaccines. Results will help determine t…

This study tested the RTS,S/AS01E malaria vaccine in over 77,000 young children across sub-Saharan Africa. Researchers checked the vaccine's safety and how well it prevents malaria as part of routine childhood shots. The goal is to protect children from this serious disease.

This early-stage trial tested a new vaccine (PRIMVAC) designed to prevent malaria in pregnant women. It involved 68 healthy adults in France and Burkina Faso to check safety and immune response. Participants received three doses of the vaccine with different adjuvants to boost ef…

This study tested whether giving a single round of the drug tafenoquine to everyone in three villages in Myanmar could safely reduce cases of a type of malaria called P. vivax. Over 1,200 people took part. The goal was to see if this approach is safe and practical in a region whe…

This study looked at whether finding and treating low-density malaria infections (infections with very few parasites) in children can improve their health and well-being over time. 600 children in Tanzania were involved. The goal was to see if this approach reduces illness, anemi…

This study tested whether giving malaria medicine to everyone in a community, even those without symptoms, can lower malaria rates in children under 15 and pregnant women. Over 3,300 people took part, and all household members received treatment after testing. The goal was to red…

This study in Tanzania looked at whether specially designed homes can help prevent malaria, respiratory infections, and diarrhea in children under 13. Over 1,100 children took part, and researchers tracked how often they got sick over a year. The goal was to see if better housing…

This study tested giving infants antimalarial medicine alongside their routine vaccinations to prevent malaria. Over 94,000 children in Mozambique, Sierra Leone, and Togo received up to 6 doses during their first two years. The goal was to see if this approach is practical and ef…

This study tested whether giving pregnant women a combination of two malaria drugs (sulfadoxine-pyrimethamine and dihydroartemisinin-piperaquine) every 4 weeks works better than either drug alone to prevent serious birth problems. Over 2,700 HIV-negative pregnant women in Uganda …

This study tested two kinds of long-lasting insecticide-treated bed nets to see which better prevents malaria in Uganda. Over 200,000 people took part, and researchers tracked malaria cases at health clinics. The goal is to find the most effective net to protect communities from …

This study tested a single injection of a lab-made antibody called L9LS in healthy Kenyan children aged 5 months to 10 years. The goal was to see if it is safe and can protect against malaria caused by the Plasmodium falciparum parasite. Over 900 children took part, and researche…

This study surveyed 222 healthcare workers in Sudan to understand what they know and think about the malaria vaccine. Researchers asked about awareness, safety, and willingness to recommend the vaccine. The results will help design programs to increase vaccine use and reduce mala…

This study measured how common malaria and worm infections are in pregnant women and young children in two counties of Liberia. Over 1,200 participants gave a small blood sample for testing. The goal was to gather information to help understand and fight these diseases.

This study tracked how often people of all ages in Sabou, Burkina Faso get malaria over one year. Researchers collected monthly blood samples and mosquito data from 608 healthy volunteers aged 6 months to 65 years. The goal was to measure infection rates by age group, which will …

This study tested a new experimental malaria drug called MMV367 in 12 healthy adults. Participants were intentionally infected with a controlled, low-level malaria infection to see how well the drug kills the parasite and how safe it is. The goal was to understand the right dose …

This study looked at how people's immune systems react to mosquito saliva after being bitten. Researchers wanted to find markers in the blood that show if someone has been exposed to mosquitoes that carry malaria or dengue. The goal is to use these markers to better track and pre…

This study looked at whether adults with type 2 diabetes in Cameroon are more likely to get malaria and other parasitic infections. Researchers followed 406 people with and without diabetes for one year, testing blood and stool samples. The goal was to understand how diabetes and…