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New drug combo could slash pregnancy risks from malaria

NCT ID NCT04336189

First seen Nov 06, 2025 · Last updated May 20, 2026 · Updated 28 times

Summary

This study tested whether giving pregnant women a combination of two malaria drugs (sulfadoxine-pyrimethamine and dihydroartemisinin-piperaquine) every 4 weeks works better than either drug alone to prevent serious birth problems. Over 2,700 HIV-negative pregnant women in Uganda took part. The goal was to see if the combo could lower the risk of miscarriage, stillbirth, low birth weight, preterm birth, and newborn death.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Infectious Diseases Research Collaboration Clinic - Masafu Hospital

    Masafu, Busia, Uganda

Conditions

Explore the condition pages connected to this study.