MAJOR DEPRESSIVE DISORDER
Clinical trials for MAJOR DEPRESSIVE DISORDER explained in plain language.
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New hope for stubborn depression? Long-Term drug trial explored
Disease control TerminatedThis study aimed to see if the drug AXS-05 is safe and effective for long-term use in adults with major depression that hasn't improved with other treatments. It involved 181 participants at multiple locations. The trial was open-label, meaning both the participants and doctors k…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE2 • Sponsor: Axsome Therapeutics, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New hope for stubborn depression? Add-On drug trial seeks better relief
Disease control TerminatedThis study tested whether a new drug called REL-1017 could help people with major depression who were still struggling despite taking standard antidepressant medication. Participants continued their usual medication and were randomly assigned to also take either REL-1017 or a pla…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for Tough-to-Treat depression? trial tests Add-On pill
Disease control TerminatedThis study tested whether a daily pill called REL-1017 could help people with major depression who weren't getting enough relief from their current antidepressant. Participants took either the new pill or a placebo (sugar pill) for four weeks while continuing their regular medica…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Brainwave test aims to end guesswork in PTSD medication
Diagnosis TerminatedThis study tested whether a simple brainwave test could predict which veterans with PTSD or depression would benefit from common antidepressant medications (SSRIs). The goal was to help doctors choose the right treatment faster, moving away from the current trial-and-error approa…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Diagnosis
Last updated Apr 04, 2026 00:20 UTC
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New app aims to help veterans at risk of suicide by teaching them to recognize their feelings
Symptom relief TerminatedThis study tested a new program for veterans with serious mental illness who are at risk of suicide. The program combined weekly group education with a smartphone app designed to help people better recognize and understand their own emotions, a skill linked to lower suicide risk.…
Matched conditions: MAJOR DEPRESSIVE DISORDER
Phase: PHASE1 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 02, 2026 14:56 UTC