LUNG CARCINOMA

This study looks at whether finding and treating COPD early can help people who are also being checked for lung cancer. About 280 adults with breathing problems will get either standard care or extra COPD treatment. The goal is to see if this improves symptoms, quality of life, a…

This study tests whether artificial intelligence can help doctors choose the right radiation dose for each person's lung tumor. About 70 adults with lung cancer or tumors that spread to the lung will receive stereotactic body radiation therapy (SBRT) with doses guided by an AI to…

This study tests a new drug called SKB518 in 192 people with lung cancer. The goal is to see if it shrinks tumors and is safe. Participants receive the drug until their disease gets worse or side effects become too strong.

This study looks at whether a home-based blood test (liquid biopsy) can make lung cancer screening easier for high-risk smokers aged 50-80. Instead of going to a clinic for a CT scan, participants collect a blood sample at home to check for cancer DNA. If the test finds signs of …

This study tests a dye called panitumumab-IRDye800 that attaches to lung cancer cells and makes them glow under a special camera during surgery. The goal is to help surgeons see and remove all cancer tissue more accurately. About 30 adults with lung cancer or lung metastases will…

This study tests whether community health advocates can help more people get screened for breast and lung cancer. Researchers will work with 800 eligible adults to see if support from friends and family increases screening rates. The goal is to understand and overcome barriers, e…

This study tests whether the drug canakinumab can prevent lung cancer in people who have suspicious lung nodules that haven't gone away. About 50 participants will receive the drug to see if their nodules shrink or disappear, and to track how many develop lung cancer over time. T…

This study tests whether giving cancer treatment at home is preferred over going to a clinic. It involves 27 adults with various cancers in the Florida Panhandle. The goal is to see if home care improves patient satisfaction and is safe.

This study tests whether telephone-based physical activity coaching helps older adults (65+) recovering from lung cancer surgery and their caregivers improve physical function compared to self-monitored activity. Participants will wear a pedometer and complete surveys and tests l…

This study looks at whether giving veterans with lung cancer extra support can help them feel better day-to-day. About 194 veterans will take part, and researchers will track their quality of life using surveys. The goal is to see if simple added help can make a real difference.

This study is testing new blood tests that look for signs of many different cancers at the same time. The goal is to see if these tests can find cancer early, when treatment works best. About 24,000 adults aged 45 to 75 who do not have cancer will take part. They will be placed i…

This study is gathering information on side effects from proton therapy in 5,000 adults with various cancers. Researchers will collect detailed treatment and toxicity data to better understand and predict short- and long-term side effects. The goal is to improve future patient ca…

This study tests whether providing education and counseling to doctors and patients can increase lung cancer screening in people with a history of smoking. About 822 participants will take part. The goal is to catch lung cancer earlier, when it may be easier to treat.

This study looks at whether low-dose CT scans are a good way to screen for lung cancer in Black individuals aged 50-80 who have smoked. Researchers want to see if this group will take part in screening and how well the scans find cancer. The goal is to improve early detection in …

This study tests whether a new screening tool can help people with advanced lung cancer better understand their disease and treatment options. About 100 patients will either use the tool or receive usual care. The goal is to see if the tool leads to more informed decisions that m…

This study tests whether a CPAP machine (commonly used for sleep apnea) can reduce tumor movement in the lungs during radiation therapy for lung cancer. About 30 participants will receive stereotactic body radiation therapy (SBRT) while using either CPAP or a deep breath-holding …

This study reviews medical records from 600 lung cancer patients who had surgery between 2004 and 2019. Researchers want to see if the use of robotic surgery has led to more atypical segmentectomies (removing part of a lung lobe). The goal is to understand trends, not to test a n…

This early-phase study tests whether a new radioactive tracer can help doctors see tumors on PET/CT scans. About 32 adults with different solid tumors will receive a single injection of the tracer. The goal is to understand where the tracer goes in the body, how it is cleared, an…

This study tests whether an online platform helps cancer patients track medication safety events and concerns while taking oral anticancer drugs at home. About 80 adults with lung, colorectal, breast, or prostate cancer will use the system to log symptoms and issues. Researchers …

This study uses robotic biopsies to collect tissue samples from people with suspected or high-risk lung cancer. The goal is to analyze the samples for genetic changes that might help diagnose cancer and build a databank for future research. About 40 adults scheduled for a standar…

This study is testing a program called CONNECTing to LungCare that helps smokers and their doctors have better conversations about quitting smoking and getting screened for lung cancer. The program provides education and a personalized summary to guide these discussions. Research…

This study looks at how walking and sleeping habits affect recovery after lung cancer surgery. Researchers will give some patients a Fitbit to track their steps and sleep. The goal is to learn if more walking leads to fewer complications and better quality of life after surgery.

This study uses special PET/CT scans to see how radiation therapy for lung or esophageal cancer affects the heart. About 20 adults getting radiation will have heart scans before, during, and after treatment. The goal is to learn if these scans can detect heart changes caused by r…

This study looks at the best ways to teach heavy smokers about lung cancer screening using tobacco quitlines. Researchers will work with 800 people, including quitline staff and smokers aged 55-80 with a heavy smoking history. The goal is to see how well these methods help smoker…