LUNG ADENOCARCINOMA

This early-stage study is testing a new type of cell therapy for people with advanced solid tumors, including melanoma, that have spread and are not responding to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack c…

This early safety study is testing if a diabetes drug called dapagliflozin is safe to give to people with early-stage lung cancer before their surgery. Researchers want to see if taking the pill for 30 days before the operation helps make the surgery more effective by reducing ca…

This study is testing a new approach for patients with advanced, inoperable lung cancer who have no other treatment options left. It combines a precise, high-dose radiation technique that targets only part of the tumor with an immunotherapy drug the patient has already tried. The…

This study is testing a new oral drug called TNG260, given alone and with the immunotherapy pembrolizumab, for people with advanced solid tumors that have a specific genetic change (STK11 mutation). The main goals are to find a safe and effective dose and to see if the treatment …

This study is testing if adding a tumor-freezing procedure (cryoablation) to standard drug therapy helps people with advanced lung cancer live longer. It will enroll 214 patients who will be randomly assigned to receive either the standard drugs alone or the drugs plus the freezi…

This study is testing whether adding an experimental drug called TRC102 to standard treatment helps people with stage III non-squamous non-small cell lung cancer live longer without their cancer getting worse. About 42 participants will receive either the standard treatment (chem…

This study is testing a new, experimental cancer drug called AZD5335 to see if it is safe and if it can help control advanced cancers. It will be given alone and in combination with other cancer drugs to adults with ovarian, lung, or endometrial cancers that have progressed despi…

This study is testing if following a special low-carb, high-fat (ketogenic) diet for one week before a PET/CT scan can help doctors better see a specific type of lung cancer that is often missed. About 30 adults with a suspicious lung nodule will try the diet and then get scanned…

This study aims to find new markers in the fluid that builds up around the lungs (pleural effusion) to help doctors better diagnose lung adenocarcinoma. Researchers will compare fluid samples from 100 patients with and without this type of lung cancer. The goal is to develop a mo…

This study is testing a new type of PET scan to see if it can detect lung cancer earlier and more accurately. Researchers will give 60 participants a special radioactive glucose tracer and then perform a PET/CT scan. The goal is to see if this new method is safe and works better …

This study is testing whether yoga and mindfulness training can help improve the quality of life for people who have survived lung, colon, or non-Hodgkin's lymphoma cancer. Researchers will enroll 100 adult survivors who finished their main cancer treatments at least six months a…

This study is testing whether weekly phone calls from a trained support worker can improve the quality of life for Veterans with lung cancer. About 194 Veterans will be randomly assigned to either receive these support calls in addition to their usual care, or to receive only the…

This large Ohio study aims to see if advanced genetic testing of tumors helps people with advanced lung cancer live longer compared to usual care. Researchers will enroll over 3,500 participants with stage IV lung cancer to compare two approaches: one group gets detailed tumor te…