LOCALLY ADVANCED RECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED RECTAL CARCINOMA explained in plain language.
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New hope for hard-to-treat rectal cancer? drug combo trial launches
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (serplulimab) and an anti-inflammatory drug (celecoxib) to standard chemotherapy can shrink locally advanced rectal cancer before surgery. It is for people with a specific type of rectal cancer (pMMR/MSS) that usually does not…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated May 26, 2026 11:34 UTC
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Immunotherapy boosts standard treatment for rectal cancer in new trial
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug tislelizumab to standard chemoradiation helps more people with locally advanced rectal cancer achieve a complete response. About 375 adults will receive either chemoradiation alone or combined with tislelizumab, followed by c…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Beijing Friendship Hospital • Aim: Disease control
Last updated May 26, 2026 11:25 UTC
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New combo aims to save rectum from surgery in rectal cancer patients
Disease control Recruiting nowThis early-phase study tests whether a short course of radiation followed by chemotherapy can shrink advanced rectal tumors enough to avoid surgery. About 25 people with stage II or III rectal cancer will receive this treatment. The goal is to preserve the rectum and improve qual…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 11:09 UTC
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Heat therapy boosts rectal cancer treatment in new trial
Disease control Recruiting nowThis phase 3 trial tests whether adding a special heat treatment (modulated electro-hyperthermia) to standard therapy helps shrink tumors more in adults with locally advanced rectal cancer. About 126 participants will be randomly assigned to receive standard therapy alone or with…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE3 • Sponsor: Shih-Kai Hung • Aim: Disease control
Last updated May 18, 2026 12:08 UTC
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New scan could better reveal rectal Cancer's response to treatment
Diagnosis Recruiting nowThis early-phase study tests a special PET scan using a substance called 64Cu-M5A to see how well it shows tumor activity in people with advanced rectal cancer. About 15 participants will get the scan before and after standard chemotherapy and radiation, and the results will be c…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated May 26, 2026 11:34 UTC