LOCALLY ADVANCED RECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED RECTAL CARCINOMA explained in plain language.
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Triple-Drug chemo may help rectal cancer patients skip surgery
Disease control OngoingThis study compares a three-drug chemotherapy combination (FOLFIRINOX) against standard two-drug combinations (FOLFOX or CAPOX) after radiation in people with stage II or III rectal cancer. The goal is to see if the stronger regimen leads to a complete disappearance of the tumor,…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 26, 2026 11:09 UTC
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Could less be more? new study tests smaller surgery for rectal cancer
Disease control OngoingThis study looks at whether people with advanced upper rectal cancer can have a smaller surgery after receiving pre-surgery therapy. About 874 adults will be randomly assigned to either standard or reduced surgical margins. The goal is to see if the smaller approach is as safe an…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: NA • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Smart scans and blood tests could spare rectal cancer patients from surgery
Knowledge-focused OngoingThis study tests whether MRI scans and blood tests can help doctors adjust treatment for locally advanced rectal cancer. About 40 participants will be monitored during chemotherapy and radiation to see if their tumors respond. The goal is to develop a non-invasive way to predict …
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Sponsor: Jena University Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Exercise may boost radiotherapy for rectal cancer patients
Knowledge-focused TerminatedThis study aimed to see if a 7-week exercise program (aerobic and resistance training) is feasible for people with locally advanced rectal cancer who are receiving short-course radiotherapy. The goal was to test if patients could stick with the exercise routine and to gather init…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: NA • Sponsor: University of Hull • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC