LOCALLY ADVANCED RECTAL CARCINOMA
Clinical trials for LOCALLY ADVANCED RECTAL CARCINOMA explained in plain language.
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Can less surgery be enough for rectal cancer?
Disease control OngoingThis study is testing whether surgeons can safely remove less healthy tissue around a rectal tumor after initial drug treatment. It will compare a smaller surgical margin to the standard larger one in about 874 patients. The main goal is to see if the smaller surgery works as wel…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: NA • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Could exercise boost cancer treatment? study tests new approach
Disease control TerminatedThis study aimed to see if adding a structured exercise program to standard short-course radiotherapy is a practical approach for people with locally advanced rectal cancer. It planned to enroll about 30 patients to complete aerobic and strength training for 7 weeks, surrounding …
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: NA • Sponsor: University of Hull • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Stronger chemo cocktail tested to help rectal cancer patients avoid surgery
Disease control OngoingThis trial is testing whether a three-drug chemotherapy combination (FOLFIRINOX) works better than the standard two-drug combinations (FOLFOX or CAPOX) for patients with locally advanced rectal cancer. All patients first receive radiation with chemo, then are randomly assigned to…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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Scientists track Cancer's response to treatment in real time
Knowledge-focused OngoingThis study aims to develop better methods for monitoring how rectal cancer responds to chemotherapy and radiation treatment. Researchers will track 40 patients using repeated MRI scans and blood tests to detect cancer cells during their treatment. The goal is to create a model th…
Matched conditions: LOCALLY ADVANCED RECTAL CARCINOMA
Sponsor: Jena University Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC