LIVER NEOPLASMS

This study is testing a treatment called BSJ019T in 51 Japanese adults with liver cancer that cannot be removed by surgery and has not responded to or is not suitable for standard treatments. The main goal is to see if the treatment can control the cancer in the liver for at leas…

This study tests a new medicine, PF-08634404, given alone or with another drug (ipilimumab) for adults with advanced liver cancer that cannot be removed by surgery. The goal is to see if the treatment is safe and shrinks tumors. About 138 participants will receive the drug throug…

This study watches how a device called HistoSonics Edison uses sound waves to destroy liver tumors in real-world settings. Up to 5000 adults with liver tumors will be tracked for up to 5 years. The goal is to see how well the treatment works and how different patients respond.

This study tests a new drug called AST-201 in people with advanced solid tumors that have a protein called GPC3. The main goal is to check the drug's safety and find the right dose. About 70 adults with liver or lung cancer that has not responded to other treatments will take par…

This study is for people with advanced liver cancer that cannot be removed by surgery. It combines a precise type of radiation (carbon ion radiotherapy) with two standard drugs (atezolizumab and bevacizumab) to see if the radiation helps control the tumor better. About 52 adults …

This study tests a powerful mix of treatments for people with advanced liver cancer that cannot be surgically removed. The approach combines tumor destruction (ablation), targeted therapy (lenvatinib), immunotherapy (tislelizumab), and a procedure that blocks the tumor's blood su…

This study tests whether contrast-enhanced ultrasound (CEUS) can accurately show how well liver tumors are responding to a treatment called chemoembolization (TACE). Currently, doctors wait 1-2 months after TACE and use MRI or CT scans to check. CEUS can be done during the proced…

This study is testing a new ultrasound technique called Contrast Enhanced Super-Resolution (CESR) imaging to see if it can better find and tell apart cancerous and non-cancerous lesions in the breast, liver, and kidney. About 40 people will take part, including 10 healthy volunte…

This study compares two types of anesthesia—spinal and epidural—for people having liver surgery. The goal is to see if spinal anesthesia leads to better blood pressure control, less need for IV fluids, and similar pain relief, helping patients recover faster. About 128 adults und…

This study is looking at whether certain substances in the blood can help doctors predict how well a liver cancer treatment called TACE is working. Researchers will follow 15 adults with liver cancer who are scheduled for TACE. They will take blood samples before and after treatm…

This study is testing whether a camera can accurately measure heart rate, blood pressure, and oxygen levels without touching the patient during surgery. About 315 adults having gallbladder, liver, or hernia surgery will participate. The goal is to see if this non-contact method w…

This study is a large registry that will follow 8,000 cancer patients who receive radiation therapy guided by an MR-Linac, a machine that combines an MRI scanner with a radiation beam. The goal is to see if this technology helps people live longer, controls tumors better, and imp…