LIVER DISEASES

This study tests a stepped alcohol treatment program delivered via telemedicine for 180 adults with chronic liver disease and unhealthy alcohol use. Participants are randomly assigned to either the treatment program (motivational interviewing plus possible addiction medicine refe…

This study tests whether a personalized disease management program can help people with early liver disease (fatty liver or fibrosis) improve their liver health. About 49 participants will receive either the tailored program or standard care. The main goal is to see if the progra…

This study tests a new treatment called QEL-001, made from a patient's own cells, to prevent the body from rejecting a donated liver. The goal is to allow patients to safely stop taking anti-rejection drugs. The trial involves 33 adults who received a liver transplant 1 to 5 year…

This study looks at how things like family income, education, and social support affect the health of children after a liver transplant. Researchers will survey 500 families and interview some of them to understand the challenges they face. The goal is to find ways to help all ch…

This study follows 300 patients with severe alcoholic hepatitis who receive an early liver transplant (before 6 months of sobriety). Researchers track survival and whether patients return to drinking within a year. The study also surveys public opinion on this practice. It aims t…

This study aims to understand how bariatric surgery improves the way the body handles sugar and fat. Researchers will collect tissue and blood samples from 500 people having weight-loss surgery or other procedures. By studying these samples, they hope to learn the molecular signa…

This study followed children and young adults with genetic liver diseases that cause bile buildup (cholestasis), including Alagille syndrome and alpha-1 antitrypsin deficiency. Researchers tracked disease progression, such as need for liver transplant or growth problems, to bette…

This study planned to test a technique that uses heat to seal the needle track after a liver, kidney, or spleen biopsy, aiming to reduce bleeding in patients at high risk. It was withdrawn before enrolling any participants. The goal was to see how well patients and doctors tolera…