LEWY BODY DISEASE

This study is testing whether a new blood test can accurately diagnose the cause of memory problems, potentially replacing the need for a spinal tap. Researchers will compare blood test results with standard spinal fluid tests in 1,200 people at a memory clinic. If successful, it…

This study is testing a special PET scan (18F-DOPA) to see if it can better detect and measure several conditions, including congenital hyperinsulinism in children, neuroblastoma, neuroendocrine tumors, Parkinson's disease, Lewy body dementia, and brain tumors. About 800 children…

This study is testing a new, non-invasive eye scan that uses different colors of light to look for signs of brain diseases like Alzheimer's, Parkinson's, and dementia. Researchers will scan the eyes of 930 adults aged 30 and older, including those with these conditions and health…

This study looks at language problems in people with Lewy body disease (like Parkinson's or dementia with Lewy bodies) who also have mild cognitive impairment. Researchers will first compare how these individuals understand sentences versus healthy older adults. Then, they will t…

This pilot study tests whether a non-invasive brain stimulation technique called tDCS can reduce psychotic-like symptoms (like hallucinations and agitation) in people with Lewy Body Dementia. Thirty participants will receive either real or sham stimulation over two weeks. Researc…

This study is following 650 people with either early Parkinson's disease or a sleep condition called idiopathic REM sleep behavior disorder (iRBD). Researchers are using brain scans, heart tests, and fluid samples to track how the disease changes over time. The goal is to better …

This study looks at how the brain, memory, thinking, and movement change over time in people with Lewy body disease, Alzheimer disease, and healthy volunteers. Researchers will use brain scans, brain wave tests, and thinking assessments to learn more about these disorders. The go…

This study looks at whether special eye scans can detect changes in the retina that are linked to memory disorders like Alzheimer's or Parkinson's. Researchers will compare eye images from 450 people with and without memory complaints. The goal is to find non-invasive markers tha…

This study follows nearly 3,000 people, including healthy volunteers and those with memory or movement problems, to track how brain diseases like Alzheimer's and Parkinson's develop over time. Researchers use advanced brain scans and tests to find early signs of disease. The goal…

This study is testing whether simple blood tests and brain scans can help doctors in primary care detect Alzheimer's disease and other memory disorders earlier and more accurately. Researchers will recruit 1,200 adults with mild memory or thinking complaints. The goal is to impro…

This study aims to better understand Lewy body disease, a brain disorder causing thinking and behavior problems that is often hard to diagnose. Researchers will analyze past EEG brain activity recordings from 40 adults to see if the brain's flexibility (how easily it changes stat…