LEPTOMENINGEAL METASTASIS
Clinical trials for LEPTOMENINGEAL METASTASIS explained in plain language.
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New hope for brain metastases: targeted drug trial launches
Disease control Not yet recruitingThis study tests an experimental drug called SHR-A1811 in 51 women with HER2-positive breast cancer that has spread to the brain. It aims to see if the drug is safe and can shrink or control brain tumors, including cases where cancer has reached the lining of the brain. Participa…
Matched conditions: LEPTOMENINGEAL METASTASIS
Phase: PHASE1, PHASE2 • Sponsor: Peking University Cancer Hospital & Institute • Aim: Disease control
Last updated May 26, 2026 08:00 UTC
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New hope for lung cancer patients with brain lining spread: drug combo trial launches
Disease control Not yet recruitingThis study tests a combination of two treatments for people with a specific type of lung cancer (NSCLC with EGFR mutation) whose cancer has spread to the lining of the brain or spinal cord (leptomeningeal metastasis) after prior targeted therapy. The treatment combines an oral dr…
Matched conditions: LEPTOMENINGEAL METASTASIS
Phase: PHASE2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Experimental vaccine combo targets brain metastases in first human trial
Disease control Not yet recruitingThis early-phase study tests whether a special cancer vaccine (SV-BR-1-GM) combined with an immunotherapy drug (pembrolizumab) is safe and feasible for people with solid tumors that have spread to the brain or spinal cord. About 20 adults whose cancer has worsened after standard …
Matched conditions: LEPTOMENINGEAL METASTASIS
Phase: PHASE1 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 19, 2026 11:47 UTC