KNEE PAIN CHRONIC
Clinical trials for KNEE PAIN CHRONIC explained in plain language.
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10-Year knee replacement study tracks 737 patients
Disease control OngoingThis study is tracking how well Persona knee replacement implants perform over time in people with severe knee arthritis. Researchers are following 737 patients for up to 10 years after surgery to see how long the implants last and how much pain relief and improved function they …
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Custom-Fit knee implants put to the test in Decade-Long study
Disease control OngoingThis study is following 240 people for 10 years after they receive a specific brand of personalized knee replacement. Researchers want to see how safe the implant is and how well it relieves pain and improves movement for people with severe knee arthritis. The study tracks patien…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Knee replacement showdown: cemented vs cementless implants
Disease control OngoingThis study compares two types of knee replacement implants—one that uses bone cement and one that doesn't—to see which provides better long-term results. Researchers will follow 300 patients with severe knee arthritis for up to 5 years after surgery, measuring pain levels, knee f…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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New knee implant aims to ease arthritis pain
Disease control OngoingThis study is testing how well a specific partial knee replacement implant works for people with arthritis on the inner side of their knee. It follows 269 patients for up to 5 years after surgery to measure changes in pain, knee function, and daily activities. Researchers will al…
Matched conditions: KNEE PAIN CHRONIC
Sponsor: Medacta USA • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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Spinal stimulator offers new hope for stubborn knee arthritis pain
Symptom relief OngoingThis study is testing whether a small implanted device that gently stimulates spinal nerves can reduce chronic pain from knee osteoarthritis. It involves 30 adults with persistent knee pain who haven't gotten enough relief from standard treatments like physical therapy or injecti…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Kenneth B Chapman • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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Could a simple conversation tool transform knee pain treatment?
Symptom relief OngoingThis study is testing a tool to help patients with knee pain or arthritis set clear, personal goals for their treatment. Researchers want to see if this goal-setting process helps patients feel more satisfied with their care and more involved in making decisions with their surgeo…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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New surgical technique aims to ease chronic knee pain
Symptom relief OngoingThis study is testing whether a small change during knee replacement surgery can reduce long-term pain. During the operation, surgeons will either tuck away the end of a specific nerve or leave it as usual. Researchers want to see if protecting this nerve helps patients experienc…
Matched conditions: KNEE PAIN CHRONIC
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Last hope: one Man's own cells injected to fight debilitating knee pain
Symptom relief NO_LONGER_AVAILABLEThis was a special access program for one individual with severe, untreatable pain in both knees from arthritis. The goal was to see if using the patient's own stem cells, given through an IV and injections directly into the knees, was safe and could reduce pain. The patient rece…
Matched conditions: KNEE PAIN CHRONIC
Sponsor: Hope Biosciences Research Foundation • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC