KNEE PAIN CHRONIC

This study follows 737 people who received a Persona knee replacement to see how well the implant works over time. Participants had severe knee pain from conditions like arthritis or injury. The goal is to measure implant survival and improve knee function.

This study compares two types of total knee replacements: one that uses bone cement to hold the implant in place and one that does not. The goal is to see which approach provides better pain relief, function, and implant survival over time. About 300 people with knee pain from ar…

This study looks at how well a knee replacement device called MOTO Medial® works for people with knee osteoarthritis. About 269 adults who need partial knee replacement will be followed for several years. Researchers will measure pain, movement, and how long the implant lasts usi…

This study is testing a new knee implant called Persona Ti-Nidium in 240 adults who need a total knee replacement due to arthritis or other knee problems. The goal is to see if the implant is safe and helps people move better and feel less pain. Participants will have surgery and…

This study tests whether protecting a nerve in the knee during total knee replacement surgery can lower chronic pain afterward. About 178 adults having a first knee replacement took part. Doctors compared the standard approach to one where the nerve end is proactively protected, …

This study looks at whether adding a gentle brain stimulation technique (tDCS) to personalized physical therapy can better relieve chronic knee pain and improve movement compared to physical therapy alone. About 30 adults with knee pain lasting over 3 months will receive either r…

This study tests a nerve stimulation device (DRG-S) to treat chronic knee pain from osteoarthritis in 30 adults. Participants have had pain for at least a year and either want to avoid knee replacement or are not candidates for it. The main goal is to see if at least half of pati…

This study tests a simple goal-setting tool for people with knee pain or injury who are seeing an orthopedic surgeon. The tool helps patients identify specific, measurable, and time-bound goals for their treatment. The goal is to improve shared decision-making and make sure patie…

This study tested a stem cell treatment in one person with long-term knee pain from osteoarthritis who had no other options left. The patient received stem cells from their own fat, given through a vein and directly into both knees. The goal was to see if it is safe and if it can…